Traitement de la rupture iatrogène des membranes fœtales par « patch » amniotique: Amniopatch to treat iatrogenic rupture of the fetal membranes

J. Deprest, T. Van Mieghem, M. P. Emonds, J. Richter, P. De Koninck, S. Zia, J. Van Keirsbilck, I. Sandaite, S.W. Olde Damink, L. Lewi

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVE: With the increased use of invasive fetal procedures, the number of patients facing postprocedure membrane rupture is increasing. We aimed to describe the use of platelets and fresh frozen plasma for sealing iatrogenic fetal membrane defects. PATIENTS AND METHODS: We describe the mechanisms of action of the amniopatch procedure as well as published experience. RESULTS: Amniopatch effectively sealed the fetal membranes in over two thirds of published cases (n=44). There is a risk of 17% of in utero fetal death, which may occur remotely from the procedure and is often unexplained. DISCUSSION AND CONCLUSION: In case of early onset but persistent amniotic fluid leakage following an invasive fetal procedure, amniopatch may be offered.
Original languageFrench
Pages (from-to)378-382
Number of pages5
JournalGynécologie Obstétrique & Fertilité
Volume39
Issue number6
DOIs
Publication statusPublished - Jun 2011

Keywords

  • Platelets
  • Fresh frozen plasma
  • Fetal surgery
  • Rupture of the membranes
  • Amniopatch
  • PRETERM PREMATURE RUPTURE
  • TWIN TRANSFUSION SYNDROME
  • FETOSCOPIC ACCESS SITES
  • RABBIT MODEL
  • GENETIC AMNIOCENTESIS
  • CRYOPRECIPITATE AMNIOPATCH
  • INTRAAMNIOTIC INJECTION
  • OBSTRUCTIVE UROPATHY
  • POTENTIAL TREATMENT
  • AMNIOTIC MEMBRANES

Cite this

Deprest, J., Van Mieghem, T., Emonds, M. P., Richter, J., De Koninck, P., Zia, S., Van Keirsbilck, J., Sandaite, I., Olde Damink, S. W., & Lewi, L. (2011). Traitement de la rupture iatrogène des membranes fœtales par « patch » amniotique: Amniopatch to treat iatrogenic rupture of the fetal membranes. Gynécologie Obstétrique & Fertilité, 39(6), 378-382. https://doi.org/10.1016/j.gyobfe.2011.04.010