Towards a "prescribing license" for medical students: development and quality evaluation of an assessment for safe prescribing

David R. M. Jansen*, Carolina J. P. W. Keijsers, Michiel O. Kornelissen, Marcel G. M. Olde Rikkert, Cornelis Kramers, J. Tichelaar, B. Janssen, A. Maassen van den Brink, L. Peeters, G. Dumont, M. Hessel, R. Rissmann, W. Knol, Education working group of the Dutch Society for Clinical Pharmacology and Biopharmacy

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Purpose This report describes the development and validation process of an assessment with national consensus in appropriate and safe pharmacotherapy. Methods A question-database on safe prescription based on literature of pharmacotherapy-related harm was developed by an expert group from Dutch medical faculties. Final-year medical students concluded a 2-year education program on appropriate and safe prescription by one of nine assessment variants of 40 multiple-choice questions each. An expert panel of professionals (n = 10) answered all database questions and rated questions on relevance. Questions were selected for revision based on lack of relevance or poor test and item characteristics. Results A total of 576 final-year medical students of the Radboud University was assessed. There was no significant difference in performance between students and content expert group (p = 0.7), probably due to learning behavior. Out of 165 questions, 59 were selected for revision. Conclusion Joint national effort from a team of experts in prescription and pharmacotherapy is an appropriate way to achieve a valid and reliable last-year student drug prescription assessment.

Original languageEnglish
Pages (from-to)1261-1268
Number of pages8
JournalEuropean Journal of Clinical Pharmacology
Issue number9
Publication statusPublished - Sept 2019


  • Prescribing
  • Medication safety
  • Education
  • HARM


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