Total, red and processed meat consumption and human health: an umbrella review of observational studies

Giuseppe Grosso; Sandro La Vignera; Rosita A. Condorelli; Justyna Godos; Stefano Marventano; Maria Tieri; Francesca Ghelfi; Lucilla Titta; Alessandra Lafranconi; Angelo Gambera; Elena Alonzo; Salvatore Sciacca; Silvio Buscemi; Sumantra Ray; Daniele Del Rio; Fabio Galvano

doi:10.1080/09637486.2022.2050996

Total, red and processed meat consumption and human health: an umbrella review of observational studies

Giuseppe Grosso^*, Sandro La Vignera, Rosita A. Condorelli, Justyna Godos, Stefano Marventano, Maria Tieri, Francesca Ghelfi, Lucilla Titta, Alessandra Lafranconi, Angelo Gambera, Elena Alonzo, Salvatore Sciacca, Silvio Buscemi, Sumantra Ray, Daniele Del Rio, Fabio Galvano

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

Meat consumption has represented an important evolutionary step for humans. However, modern patterns of consumption, including excess intake, type of meat and cooking method have been the focus of attention as a potential cause of rise in non-communicable diseases. The aim of this study was to investigate the association between total, red and processed meat with health outcomes and to assess the level of evidence by performing a systematic search of meta-analyses of prospective cohort studies. Convincing evidence of the association between increased risk of (i) colorectal adenoma, lung cancer, CHD and stroke, (ii) colorectal adenoma, ovarian, prostate, renal and stomach cancers, CHD and stroke and (iii) colon and bladder cancer was found for excess intake of total, red and processed meat, respectively. Possible negative associations with other health outcomes have been reported. Excess meat consumption may be detrimental to health, with a major impact on cardiometabolic and cancer risk.

Original language	English
Pages (from-to)	726-737
Number of pages	12
Journal	International Journal of Food Sciences and Nutrition
Volume	73
Issue number	6
Early online date	1 Mar 2022
DOIs	https://doi.org/10.1080/09637486.2022.2050996
Publication status	Published - 18 Aug 2022

Keywords

Total meat
red meat
processed meat
processed foods
meta-analysis
umbrella review
evidence
non-communicable diseases
cardiovascular disease
cancer
coronary heart disease
colorectal cancer
DOSE-RESPONSE METAANALYSIS
ESOPHAGEAL CANCER-RISK
NON-HODGKIN-LYMPHOMA
RANDOMIZED CONTROLLED-TRIALS
ANIMAL SOURCE FOODS
COLORECTAL-CANCER
DIETARY FACTORS
BLADDER-CANCER
BREAST-CANCER
FATTY-ACIDS

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Grosso, G., La Vignera, S., Condorelli, R. A., Godos, J., Marventano, S., Tieri, M., Ghelfi, F., Titta, L., Lafranconi, A., Gambera, A., Alonzo, E., Sciacca, S., Buscemi, S., Ray, S., Del Rio, D., & Galvano, F. (2022). Total, red and processed meat consumption and human health: an umbrella review of observational studies. International Journal of Food Sciences and Nutrition, 73(6), 726-737. https://doi.org/10.1080/09637486.2022.2050996

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title = "Total, red and processed meat consumption and human health: an umbrella review of observational studies",

abstract = "Meat consumption has represented an important evolutionary step for humans. However, modern patterns of consumption, including excess intake, type of meat and cooking method have been the focus of attention as a potential cause of rise in non-communicable diseases. The aim of this study was to investigate the association between total, red and processed meat with health outcomes and to assess the level of evidence by performing a systematic search of meta-analyses of prospective cohort studies. Convincing evidence of the association between increased risk of (i) colorectal adenoma, lung cancer, CHD and stroke, (ii) colorectal adenoma, ovarian, prostate, renal and stomach cancers, CHD and stroke and (iii) colon and bladder cancer was found for excess intake of total, red and processed meat, respectively. Possible negative associations with other health outcomes have been reported. Excess meat consumption may be detrimental to health, with a major impact on cardiometabolic and cancer risk.",

keywords = "Total meat, red meat, processed meat, processed foods, meta-analysis, umbrella review, evidence, non-communicable diseases, cardiovascular disease, cancer, coronary heart disease, colorectal cancer, DOSE-RESPONSE METAANALYSIS, ESOPHAGEAL CANCER-RISK, NON-HODGKIN-LYMPHOMA, RANDOMIZED CONTROLLED-TRIALS, ANIMAL SOURCE FOODS, COLORECTAL-CANCER, DIETARY FACTORS, BLADDER-CANCER, BREAST-CANCER, FATTY-ACIDS",

author = "Giuseppe Grosso and {La Vignera}, Sandro and Condorelli, {Rosita A.} and Justyna Godos and Stefano Marventano and Maria Tieri and Francesca Ghelfi and Lucilla Titta and Alessandra Lafranconi and Angelo Gambera and Elena Alonzo and Salvatore Sciacca and Silvio Buscemi and Sumantra Ray and {Del Rio}, Daniele and Fabio Galvano",

year = "2022",

month = aug,

day = "18",

doi = "10.1080/09637486.2022.2050996",

language = "English",

volume = "73",

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Grosso, G, La Vignera, S, Condorelli, RA, Godos, J, Marventano, S, Tieri, M, Ghelfi, F, Titta, L, Lafranconi, A, Gambera, A, Alonzo, E, Sciacca, S, Buscemi, S, Ray, S, Del Rio, D & Galvano, F 2022, 'Total, red and processed meat consumption and human health: an umbrella review of observational studies', International Journal of Food Sciences and Nutrition, vol. 73, no. 6, pp. 726-737. https://doi.org/10.1080/09637486.2022.2050996

TY - JOUR

T1 - Total, red and processed meat consumption and human health

T2 - an umbrella review of observational studies

AU - Grosso, Giuseppe

AU - La Vignera, Sandro

AU - Condorelli, Rosita A.

AU - Godos, Justyna

AU - Marventano, Stefano

AU - Tieri, Maria

AU - Ghelfi, Francesca

AU - Titta, Lucilla

AU - Lafranconi, Alessandra

AU - Gambera, Angelo

AU - Alonzo, Elena

AU - Sciacca, Salvatore

AU - Buscemi, Silvio

AU - Ray, Sumantra

AU - Del Rio, Daniele

AU - Galvano, Fabio

PY - 2022/8/18

Y1 - 2022/8/18

N2 - Meat consumption has represented an important evolutionary step for humans. However, modern patterns of consumption, including excess intake, type of meat and cooking method have been the focus of attention as a potential cause of rise in non-communicable diseases. The aim of this study was to investigate the association between total, red and processed meat with health outcomes and to assess the level of evidence by performing a systematic search of meta-analyses of prospective cohort studies. Convincing evidence of the association between increased risk of (i) colorectal adenoma, lung cancer, CHD and stroke, (ii) colorectal adenoma, ovarian, prostate, renal and stomach cancers, CHD and stroke and (iii) colon and bladder cancer was found for excess intake of total, red and processed meat, respectively. Possible negative associations with other health outcomes have been reported. Excess meat consumption may be detrimental to health, with a major impact on cardiometabolic and cancer risk.

AB - Meat consumption has represented an important evolutionary step for humans. However, modern patterns of consumption, including excess intake, type of meat and cooking method have been the focus of attention as a potential cause of rise in non-communicable diseases. The aim of this study was to investigate the association between total, red and processed meat with health outcomes and to assess the level of evidence by performing a systematic search of meta-analyses of prospective cohort studies. Convincing evidence of the association between increased risk of (i) colorectal adenoma, lung cancer, CHD and stroke, (ii) colorectal adenoma, ovarian, prostate, renal and stomach cancers, CHD and stroke and (iii) colon and bladder cancer was found for excess intake of total, red and processed meat, respectively. Possible negative associations with other health outcomes have been reported. Excess meat consumption may be detrimental to health, with a major impact on cardiometabolic and cancer risk.

KW - Total meat

KW - red meat

KW - processed meat

KW - processed foods

KW - meta-analysis

KW - umbrella review

KW - evidence

KW - non-communicable diseases

KW - cardiovascular disease

KW - cancer

KW - coronary heart disease

KW - colorectal cancer

KW - DOSE-RESPONSE METAANALYSIS

KW - ESOPHAGEAL CANCER-RISK

KW - NON-HODGKIN-LYMPHOMA

KW - RANDOMIZED CONTROLLED-TRIALS

KW - ANIMAL SOURCE FOODS

KW - COLORECTAL-CANCER

KW - DIETARY FACTORS

KW - BLADDER-CANCER

KW - BREAST-CANCER

KW - FATTY-ACIDS

U2 - 10.1080/09637486.2022.2050996

DO - 10.1080/09637486.2022.2050996

M3 - (Systematic) Review article

SN - 0963-7486

VL - 73

SP - 726

EP - 737

JO - International Journal of Food Sciences and Nutrition

JF - International Journal of Food Sciences and Nutrition

IS - 6

ER -

Total, red and processed meat consumption and human health: an umbrella review of observational studies

Abstract

Keywords

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