TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC trial): study protocol for a randomized controlled trial

M. M. Koeneman*, A. J. Kruse, L. F. S. Kooreman, A. zur Hausen, A. H. N. Hopman, S. J. S. Sep, T. van Gorp, B. F. M. Slangen, H. J. van Beekhuizen, M. van de Sande, C. G. Gerestein, H. W. Nijman, R. F. P. M. Kruitwagen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number132
JournalBMC Cancer
Publication statusPublished - 20 Feb 2016


  • Cervical intraepithelial neoplasia
  • Imiquimod
  • Biological markers
  • Human papillomavirus
  • Natural history

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