Tissue sensitive imaging and tomography without contrast agents for small animals with Timepix based detectors

E. Trojanova; L. E. J. R. Schyns; L. Dubois; J. Jakubek; A. Le Pape; L. Sefc; V. Sykora; D. Turecek; J. Uher; F. Verhaegen

doi:10.1088/1748-0221/12/01/C01056

Tissue sensitive imaging and tomography without contrast agents for small animals with Timepix based detectors

E. Trojanova^*, L. E. J. R. Schyns, L. Dubois, J. Jakubek, A. Le Pape, L. Sefc, V. Sykora, D. Turecek, J. Uher, F. Verhaegen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

The tissue type resolving X-ray radiography and tomography can be performed even without contrast agents. The differences between soft tissue types such as kidney, muscles, fat, liver, brain and spleen were measured based on their spectral response. The Timepix based X-ray imaging detector WidePIX(2x5) with 300 mu m thick silicon sensors was used for most of the measurements presented in this work. These promising results are used for further optimizations of the detector technology and radiographic methods.

Original language	English
Article number	01056
Number of pages	9
Journal	Journal of Instrumentation
Volume	12
DOIs	https://doi.org/10.1088/1748-0221/12/01/C01056
Publication status	Published - Jan 2017
Event	18th International Workshop on Radiation Imaging Detectors - Barcelona, Spain Duration: 3 Jul 2016 → 7 Jul 2016

Keywords

Pixelated detectors and associated VLSI electronics
Spectral responses
X-ray detectors
X-ray radiography and digital radiography (DR)

Access to Document

10.1088/1748-0221/12/01/C01056

Full TextFinal published version, 2.61 MBLicence: Taverne

Cite this

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title = "Tissue sensitive imaging and tomography without contrast agents for small animals with Timepix based detectors",

abstract = "The tissue type resolving X-ray radiography and tomography can be performed even without contrast agents. The differences between soft tissue types such as kidney, muscles, fat, liver, brain and spleen were measured based on their spectral response. The Timepix based X-ray imaging detector WidePIX(2x5) with 300 mu m thick silicon sensors was used for most of the measurements presented in this work. These promising results are used for further optimizations of the detector technology and radiographic methods.",

keywords = "Pixelated detectors and associated VLSI electronics, Spectral responses, X-ray detectors, X-ray radiography and digital radiography (DR)",

author = "E. Trojanova and Schyns, {L. E. J. R.} and L. Dubois and J. Jakubek and {Le Pape}, A. and L. Sefc and V. Sykora and D. Turecek and J. Uher and F. Verhaegen",

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doi = "10.1088/1748-0221/12/01/C01056",

language = "English",

volume = "12",

journal = "Journal of Instrumentation",

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note = "18th International Workshop on Radiation Imaging Detectors, IWORID2016 ; Conference date: 03-07-2016 Through 07-07-2016",

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T1 - Tissue sensitive imaging and tomography without contrast agents for small animals with Timepix based detectors

AU - Trojanova, E.

AU - Schyns, L. E. J. R.

AU - Dubois, L.

AU - Jakubek, J.

AU - Le Pape, A.

AU - Sefc, L.

AU - Sykora, V.

AU - Turecek, D.

AU - Uher, J.

AU - Verhaegen, F.

PY - 2017/1

Y1 - 2017/1

N2 - The tissue type resolving X-ray radiography and tomography can be performed even without contrast agents. The differences between soft tissue types such as kidney, muscles, fat, liver, brain and spleen were measured based on their spectral response. The Timepix based X-ray imaging detector WidePIX(2x5) with 300 mu m thick silicon sensors was used for most of the measurements presented in this work. These promising results are used for further optimizations of the detector technology and radiographic methods.

AB - The tissue type resolving X-ray radiography and tomography can be performed even without contrast agents. The differences between soft tissue types such as kidney, muscles, fat, liver, brain and spleen were measured based on their spectral response. The Timepix based X-ray imaging detector WidePIX(2x5) with 300 mu m thick silicon sensors was used for most of the measurements presented in this work. These promising results are used for further optimizations of the detector technology and radiographic methods.

KW - Pixelated detectors and associated VLSI electronics

KW - Spectral responses

KW - X-ray detectors

KW - X-ray radiography and digital radiography (DR)

U2 - 10.1088/1748-0221/12/01/C01056

DO - 10.1088/1748-0221/12/01/C01056

M3 - Article

SN - 1748-0221

VL - 12

JO - Journal of Instrumentation

JF - Journal of Instrumentation

M1 - 01056

T2 - 18th International Workshop on Radiation Imaging Detectors

Y2 - 3 July 2016 through 7 July 2016

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