The traveling heads: multicenter brain imaging at 7 Tesla

Maximilian N Voelker, Oliver Kraff, Daniel Brenner, Astrid Wollrab, Oliver Weinberger, Moritz C Berger, Simon Robinson, Wolfgang Bogner, Christopher Wiggins, Robert Trampel, Tony Stöcker, Thoralf Niendorf, Harald H Quick, David G Norris, Mark E Ladd, Oliver Speck

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVE: This study evaluates the inter-site and intra-site reproducibility of 7 Tesla brain imaging and compares it to literature values for other field strengths.

MATERIALS AND METHODS: The same two subjects were imaged at eight different 7 T sites. MP2RAGE, TSE, TOF, SWI, EPI as well as B1 and B0 field maps were analyzed quantitatively to assess inter-site reproducibility. Intra-site reproducibility was measured with rescans at three sites.

RESULTS: Quantitative measures of MP2RAGE scans showed high agreement. Inter-site and intra-site reproducibility errors were comparable to 1.5 and 3 T. Other sequences also showed high reproducibility between the sites, but differences were also revealed. The different RF coils used were the main source for systematic differences between the sites.

CONCLUSION: Our results show for the first time that multi-center brain imaging studies of the supratentorial brain can be performed at 7 T with high reproducibility and similar reliability as at 3T. This study develops the basis for future large-scale 7 T multi-site studies.

Original languageEnglish
Pages (from-to)399-415
Number of pages17
JournalMagnetic Resonance Materials in Physics Biology and Medicine
Volume29
Issue number3
DOIs
Publication statusPublished - Jun 2016

Keywords

  • Magnetic resonance imaging
  • Neuroimaging
  • Ultrahigh field
  • Multi-center
  • T MRI DATA
  • PHYSIOLOGICAL NOISE
  • IMAGES
  • FIELD
  • REPRODUCIBILITY
  • SEGMENTATION
  • OPTIMIZATION
  • MORPHOMETRY
  • DEMENTIA
  • ROBUST

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