The role of the left inferior frontal gyrus in social perception: An rTMS study

Max C. Keuken, A. Hardie, B. T. Dorn, S. Dev, M. P. Paulus, K. J. Jonas, W. P. M. Van den Wildenberg, J. A. Pineda

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Perceiving and interpreting social information richness is something that humans do automatically whenever they engage in social interactions. Numerous studies have identified neural substrates, including mirror neurons that may enable such social perception. In this study, we temporarily disrupted activity in the left inferior frontal gyrus (LIFG) using repetitive transcranial magnetic stimulation (rTMS). We investigated whether this cortical region, that is hypothesized to include mirror neurons, plays a central role in social perception. The LIFG was stimulated in the experimental condition (n=18), the vertex was targeted in the control condition (n=19). Disrupting LIFG, but not vertex, increased reaction times during an emotion recognition task, and eliminated the suppression of the 8-12 Hz EEG mu rhythm, postulated as an index of mirroring activity. The results of this study provide further evidence for the role of the human mirror neuron system (MNS) in social perception, and indicate that the MNS can be measured with EEG. (C) 2011 Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)196-205
Number of pages10
JournalBrain Research
Volume1383
DOIs
Publication statusPublished - 6 Apr 2011
Externally publishedYes

Keywords

  • Mirroring
  • rTMS
  • Social perception
  • mu rhythms

Cite this

Keuken, M. C., Hardie, A., Dorn, B. T., Dev, S., Paulus, M. P., Jonas, K. J., Van den Wildenberg, W. P. M., & Pineda, J. A. (2011). The role of the left inferior frontal gyrus in social perception: An rTMS study. Brain Research, 1383, 196-205. https://doi.org/10.1016/j.brainres.2011.01.073