The resilience framework as a strategy to combat stress-related disorders

Raffael Kalisch; Dewleen G. Baker; Ulrike Basten; Marco P. Boks; George A. Bonanno; Eddie Brummelman; Andrea Chmitorz; Guillen Fernandez; Christian J. Fiebach; Isaac Galatzer-Levy; Elbert Geuze; Sergiu Groppa; Isabella Helmreich; Talma Hendler; Erno J. Hermans; Tanja Jovanovic; Thomas Kubiak; Klaus Lieb; Beat Lutz; Marianne B. Mueller; Ryan J. Murray; Caroline M. Nievergelt; Andreas Reif; Karin Roelofs; Bart P. F. Rutten; David Sander; Anita Schick; Oliver Tuescher; Ilse Van Diest; Anne-Laura van Harmelen; Ilya M. Veer; Eric Vermetten; Christiaan H. Vinkers; Tor D. Wager; Henrik Walter; Michele Wessa; Michael Wibral; Birgit Kleim

doi:10.1038/s41562-017-0200-8

The resilience framework as a strategy to combat stress-related disorders

Raffael Kalisch^*, Dewleen G. Baker, Ulrike Basten, Marco P. Boks, George A. Bonanno, Eddie Brummelman, Andrea Chmitorz, Guillen Fernandez, Christian J. Fiebach, Isaac Galatzer-Levy, Elbert Geuze, Sergiu Groppa, Isabella Helmreich, Talma Hendler, Erno J. Hermans, Tanja Jovanovic, Thomas Kubiak, Klaus Lieb, Beat Lutz, Marianne B. MuellerRyan J. Murray, Caroline M. Nievergelt, Andreas Reif, Karin Roelofs, Bart P. F. Rutten, David Sander, Anita Schick, Oliver Tuescher, Ilse Van Diest, Anne-Laura van Harmelen, Ilya M. Veer, Eric Vermetten, Christiaan H. Vinkers, Tor D. Wager, Henrik Walter, Michele Wessa, Michael Wibral, Birgit Kleim

^*Corresponding author for this work

MHeNs - Neuroscience

Research output: Contribution to journal › Article › Academic › peer-review

226 Citations (Web of Science)

Abstract

Consistent failure over the past few decades to reduce the high prevalence of stress-related disorders has motivated a search for alternative research strategies. Resilience refers to the phenomenon of many people maintaining mental health despite exposure to psychological or physical adversity. Instead of aiming to understand the pathophysiology of stress-related disorders, resilience research focuses on protective mechanisms that shield people against the development of such disorders and tries to exploit its insights to improve treatment and, in particular, disease prevention. To fully harness the potential of resilience research, a critical appraisal of the current state of the art - in terms of basic concepts and key methods - is needed. We highlight challenges to resilience research and make concrete conceptual and methodological proposals to improve resilience research. Most importantly, we propose to focus research on the dynamic processes of successful adaptation to stressors in prospective longitudinal studies.

Original language	English
Pages (from-to)	784-790
Number of pages	7
Journal	Nature human behaviour
Volume	1
Issue number	11
DOIs	https://doi.org/10.1038/s41562-017-0200-8
Publication status	Published - Nov 2017

Keywords

CUMULATIVE LIFETIME ADVERSITY
POSTTRAUMATIC GROWTH
CONCEPTUAL-FRAMEWORK
MENTAL-HEALTH
TRAUMA
RISK
GENE
SUSCEPTIBILITY
ASSOCIATIONS
INDIVIDUALS

Access to Document

10.1038/s41562-017-0200-8

Cite this

Kalisch, R., Baker, D. G., Basten, U., Boks, M. P., Bonanno, G. A., Brummelman, E., Chmitorz, A., Fernandez, G., Fiebach, C. J., Galatzer-Levy, I., Geuze, E., Groppa, S., Helmreich, I., Hendler, T., Hermans, E. J., Jovanovic, T., Kubiak, T., Lieb, K., Lutz, B., ... Kleim, B. (2017). The resilience framework as a strategy to combat stress-related disorders. Nature human behaviour, 1(11), 784-790. https://doi.org/10.1038/s41562-017-0200-8

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title = "The resilience framework as a strategy to combat stress-related disorders",

abstract = "Consistent failure over the past few decades to reduce the high prevalence of stress-related disorders has motivated a search for alternative research strategies. Resilience refers to the phenomenon of many people maintaining mental health despite exposure to psychological or physical adversity. Instead of aiming to understand the pathophysiology of stress-related disorders, resilience research focuses on protective mechanisms that shield people against the development of such disorders and tries to exploit its insights to improve treatment and, in particular, disease prevention. To fully harness the potential of resilience research, a critical appraisal of the current state of the art - in terms of basic concepts and key methods - is needed. We highlight challenges to resilience research and make concrete conceptual and methodological proposals to improve resilience research. Most importantly, we propose to focus research on the dynamic processes of successful adaptation to stressors in prospective longitudinal studies.",

keywords = "CUMULATIVE LIFETIME ADVERSITY, POSTTRAUMATIC GROWTH, CONCEPTUAL-FRAMEWORK, MENTAL-HEALTH, TRAUMA, RISK, GENE, SUSCEPTIBILITY, ASSOCIATIONS, INDIVIDUALS",

author = "Raffael Kalisch and Baker, {Dewleen G.} and Ulrike Basten and Boks, {Marco P.} and Bonanno, {George A.} and Eddie Brummelman and Andrea Chmitorz and Guillen Fernandez and Fiebach, {Christian J.} and Isaac Galatzer-Levy and Elbert Geuze and Sergiu Groppa and Isabella Helmreich and Talma Hendler and Hermans, {Erno J.} and Tanja Jovanovic and Thomas Kubiak and Klaus Lieb and Beat Lutz and Mueller, {Marianne B.} and Murray, {Ryan J.} and Nievergelt, {Caroline M.} and Andreas Reif and Karin Roelofs and Rutten, {Bart P. F.} and David Sander and Anita Schick and Oliver Tuescher and {Van Diest}, Ilse and {van Harmelen}, Anne-Laura and Veer, {Ilya M.} and Eric Vermetten and Vinkers, {Christiaan H.} and Wager, {Tor D.} and Henrik Walter and Michele Wessa and Michael Wibral and Birgit Kleim",

year = "2017",

month = nov,

doi = "10.1038/s41562-017-0200-8",

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Kalisch, R, Baker, DG, Basten, U, Boks, MP, Bonanno, GA, Brummelman, E, Chmitorz, A, Fernandez, G, Fiebach, CJ, Galatzer-Levy, I, Geuze, E, Groppa, S, Helmreich, I, Hendler, T, Hermans, EJ, Jovanovic, T, Kubiak, T, Lieb, K, Lutz, B, Mueller, MB, Murray, RJ, Nievergelt, CM, Reif, A, Roelofs, K, Rutten, BPF, Sander, D, Schick, A, Tuescher, O, Van Diest, I, van Harmelen, A-L, Veer, IM, Vermetten, E, Vinkers, CH, Wager, TD, Walter, H, Wessa, M, Wibral, M & Kleim, B 2017, 'The resilience framework as a strategy to combat stress-related disorders', Nature human behaviour, vol. 1, no. 11, pp. 784-790. https://doi.org/10.1038/s41562-017-0200-8

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AU - Kalisch, Raffael

AU - Baker, Dewleen G.

AU - Basten, Ulrike

AU - Boks, Marco P.

AU - Bonanno, George A.

AU - Brummelman, Eddie

AU - Chmitorz, Andrea

AU - Fernandez, Guillen

AU - Fiebach, Christian J.

AU - Galatzer-Levy, Isaac

AU - Geuze, Elbert

AU - Groppa, Sergiu

AU - Helmreich, Isabella

AU - Hendler, Talma

AU - Hermans, Erno J.

AU - Jovanovic, Tanja

AU - Kubiak, Thomas

AU - Lieb, Klaus

AU - Lutz, Beat

AU - Mueller, Marianne B.

AU - Murray, Ryan J.

AU - Nievergelt, Caroline M.

AU - Reif, Andreas

AU - Roelofs, Karin

AU - Rutten, Bart P. F.

AU - Sander, David

AU - Schick, Anita

AU - Tuescher, Oliver

AU - Van Diest, Ilse

AU - van Harmelen, Anne-Laura

AU - Veer, Ilya M.

AU - Vermetten, Eric

AU - Vinkers, Christiaan H.

AU - Wager, Tor D.

AU - Walter, Henrik

AU - Wessa, Michele

AU - Wibral, Michael

AU - Kleim, Birgit

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AB - Consistent failure over the past few decades to reduce the high prevalence of stress-related disorders has motivated a search for alternative research strategies. Resilience refers to the phenomenon of many people maintaining mental health despite exposure to psychological or physical adversity. Instead of aiming to understand the pathophysiology of stress-related disorders, resilience research focuses on protective mechanisms that shield people against the development of such disorders and tries to exploit its insights to improve treatment and, in particular, disease prevention. To fully harness the potential of resilience research, a critical appraisal of the current state of the art - in terms of basic concepts and key methods - is needed. We highlight challenges to resilience research and make concrete conceptual and methodological proposals to improve resilience research. Most importantly, we propose to focus research on the dynamic processes of successful adaptation to stressors in prospective longitudinal studies.

KW - CUMULATIVE LIFETIME ADVERSITY

KW - POSTTRAUMATIC GROWTH

KW - CONCEPTUAL-FRAMEWORK

KW - MENTAL-HEALTH

KW - TRAUMA

KW - RISK

KW - GENE

KW - SUSCEPTIBILITY

KW - ASSOCIATIONS

KW - INDIVIDUALS

U2 - 10.1038/s41562-017-0200-8

DO - 10.1038/s41562-017-0200-8

M3 - Article

VL - 1

SP - 784

EP - 790

JO - Nature human behaviour

JF - Nature human behaviour

SN - 2397-3374

IS - 11

ER -