The pros and cons of preserving a functioning arteriovenous fistula after kidney transplantation

Bram M. Voorzaat; Jan van Schaik; Hans-Marc J. Siebelink; Jan H. Tordoir; Joris I. Rotmans

doi:10.5301/jva.5000525

The pros and cons of preserving a functioning arteriovenous fistula after kidney transplantation

Bram M. Voorzaat, Jan van Schaik, Hans-Marc J. Siebelink, Jan H. Tordoir, Joris I. Rotmans^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The autologous arteriovenous fistula (AVF) for hemodialysis burdens the cardiovascular system with increased cardiac output and pulmonary artery pressure, increasing cardiovascular risk. This article reviews literature on the benefits and drawbacks of a functioning AVF after kidney transplantation and discusses the cardiovascular effects of AVF closure. Several cohort studies demonstrate a significant cardiac burden of an AVF and improvement of cardiac dimensions after AVF ligation. However, no randomized trials have been conducted on routine AVF closure after successful kidney transplantation. Therefore, clinical trials are warranted to evaluate whether the cardiovascular benefits of routine AVF closure outweigh the potential harm for patients after successful kidney transplantation.

Original language	English
Pages (from-to)	S16-S22
Journal	Journal of vascular access
Volume	17
Issue number	S1
DOIs	https://doi.org/10.5301/jva.5000525
Publication status	Published - Mar 2016

Keywords

Arteriovenous shunt surgical
Cardiac output
Hypertrophy left ventricular
Kidney transplantation
Renal dialysis

Access to Document

10.5301/jva.5000525

Cite this

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title = "The pros and cons of preserving a functioning arteriovenous fistula after kidney transplantation",

abstract = "The autologous arteriovenous fistula (AVF) for hemodialysis burdens the cardiovascular system with increased cardiac output and pulmonary artery pressure, increasing cardiovascular risk. This article reviews literature on the benefits and drawbacks of a functioning AVF after kidney transplantation and discusses the cardiovascular effects of AVF closure. Several cohort studies demonstrate a significant cardiac burden of an AVF and improvement of cardiac dimensions after AVF ligation. However, no randomized trials have been conducted on routine AVF closure after successful kidney transplantation. Therefore, clinical trials are warranted to evaluate whether the cardiovascular benefits of routine AVF closure outweigh the potential harm for patients after successful kidney transplantation.",

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AU - van Schaik, Jan

AU - Siebelink, Hans-Marc J.

AU - Tordoir, Jan H.

AU - Rotmans, Joris I.

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AB - The autologous arteriovenous fistula (AVF) for hemodialysis burdens the cardiovascular system with increased cardiac output and pulmonary artery pressure, increasing cardiovascular risk. This article reviews literature on the benefits and drawbacks of a functioning AVF after kidney transplantation and discusses the cardiovascular effects of AVF closure. Several cohort studies demonstrate a significant cardiac burden of an AVF and improvement of cardiac dimensions after AVF ligation. However, no randomized trials have been conducted on routine AVF closure after successful kidney transplantation. Therefore, clinical trials are warranted to evaluate whether the cardiovascular benefits of routine AVF closure outweigh the potential harm for patients after successful kidney transplantation.

KW - Arteriovenous shunt surgical

KW - Cardiac output

KW - Hypertrophy left ventricular

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