The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them

Martyn T Smith; Kathryn Z Guyton; Nicole Kleinstreuer; Alexandre Borrel; Andres Cardenas; Weihsueh A Chiu; Dean W Felsher; Catherine F Gibbons; William H Goodson; Keith A Houck; Agnes Kane; Michele A La Merrill; Herve Lebrec; Leroy Lowe; Cliona M McHale; Sheroy Minocherhomji; Linda Rieswijk; Martha S Sandy; Hideko Sone; Amy Wang; Luoping Zhang; Lauren Zeise; Mark Fielden

doi:10.1158/1055-9965.EPI-19-1346

The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them

Martyn T Smith^*, Kathryn Z Guyton, Nicole Kleinstreuer, Alexandre Borrel, Andres Cardenas, Weihsueh A Chiu, Dean W Felsher, Catherine F Gibbons, William H Goodson, Keith A Houck, Agnes Kane, Michele A La Merrill, Herve Lebrec, Leroy Lowe, Cliona M McHale, Sheroy Minocherhomji, Linda Rieswijk, Martha S Sandy, Hideko Sone, Amy WangLuoping Zhang, Lauren Zeise, Mark Fielden

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1887-1903
Number of pages	17
Journal	Cancer Epidemiology Biomarkers & Prevention
Volume	29
Issue number	10
Early online date	9 Mar 2020
DOIs	https://doi.org/10.1158/1055-9965.EPI-19-1346
Publication status	Published - Oct 2020

Keywords

ARYL-HYDROCARBON RECEPTOR
IN-SILICO PREDICTION
GENOMIC INSTABILITY
REPLICATION STRESS
OXIDATIVE STRESS
BREAST-CANCER
DNA-DAMAGE
INFLAMMATORY BIOMARKERS
CHROMOSOMAL-ABERRATIONS
REACTIVE METABOLITES

Access to Document

10.1158/1055-9965.EPI-19-1346

Cite this

Smith, M. T., Guyton, K. Z., Kleinstreuer, N., Borrel, A., Cardenas, A., Chiu, W. A., Felsher, D. W., Gibbons, C. F., Goodson, W. H., Houck, K. A., Kane, A., La Merrill, M. A., Lebrec, H., Lowe, L., McHale, C. M., Minocherhomji, S., Rieswijk, L., Sandy, M. S., Sone, H., ... Fielden, M. (2020). The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them. Cancer Epidemiology Biomarkers & Prevention, 29(10), 1887-1903. https://doi.org/10.1158/1055-9965.EPI-19-1346

Smith, Martyn T ; Guyton, Kathryn Z ; Kleinstreuer, Nicole ; Borrel, Alexandre ; Cardenas, Andres ; Chiu, Weihsueh A ; Felsher, Dean W ; Gibbons, Catherine F ; Goodson, William H ; Houck, Keith A ; Kane, Agnes ; La Merrill, Michele A ; Lebrec, Herve ; Lowe, Leroy ; McHale, Cliona M ; Minocherhomji, Sheroy ; Rieswijk, Linda ; Sandy, Martha S ; Sone, Hideko ; Wang, Amy ; Zhang, Luoping ; Zeise, Lauren ; Fielden, Mark. / The Key Characteristics of Carcinogens : Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them. In: Cancer Epidemiology Biomarkers & Prevention. 2020 ; Vol. 29, No. 10. pp. 1887-1903.

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title = "The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them",

keywords = "ARYL-HYDROCARBON RECEPTOR, IN-SILICO PREDICTION, GENOMIC INSTABILITY, REPLICATION STRESS, OXIDATIVE STRESS, BREAST-CANCER, DNA-DAMAGE, INFLAMMATORY BIOMARKERS, CHROMOSOMAL-ABERRATIONS, REACTIVE METABOLITES",

author = "Smith, {Martyn T} and Guyton, {Kathryn Z} and Nicole Kleinstreuer and Alexandre Borrel and Andres Cardenas and Chiu, {Weihsueh A} and Felsher, {Dean W} and Gibbons, {Catherine F} and Goodson, {William H} and Houck, {Keith A} and Agnes Kane and {La Merrill}, {Michele A} and Herve Lebrec and Leroy Lowe and McHale, {Cliona M} and Sheroy Minocherhomji and Linda Rieswijk and Sandy, {Martha S} and Hideko Sone and Amy Wang and Luoping Zhang and Lauren Zeise and Mark Fielden",

note = "Copyright {\textcopyright}2020, American Association for Cancer Research.",

year = "2020",

month = oct,

doi = "10.1158/1055-9965.EPI-19-1346",

language = "English",

volume = "29",

pages = "1887--1903",

journal = "Cancer Epidemiology Biomarkers & Prevention",

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Smith, MT, Guyton, KZ, Kleinstreuer, N, Borrel, A, Cardenas, A, Chiu, WA, Felsher, DW, Gibbons, CF, Goodson, WH, Houck, KA, Kane, A, La Merrill, MA, Lebrec, H, Lowe, L, McHale, CM, Minocherhomji, S, Rieswijk, L, Sandy, MS, Sone, H, Wang, A, Zhang, L, Zeise, L & Fielden, M 2020, 'The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them', Cancer Epidemiology Biomarkers & Prevention, vol. 29, no. 10, pp. 1887-1903. https://doi.org/10.1158/1055-9965.EPI-19-1346

The Key Characteristics of Carcinogens : Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them. / Smith, Martyn T; Guyton, Kathryn Z; Kleinstreuer, Nicole; Borrel, Alexandre; Cardenas, Andres; Chiu, Weihsueh A; Felsher, Dean W; Gibbons, Catherine F; Goodson, William H; Houck, Keith A; Kane, Agnes; La Merrill, Michele A; Lebrec, Herve; Lowe, Leroy; McHale, Cliona M; Minocherhomji, Sheroy; Rieswijk, Linda; Sandy, Martha S; Sone, Hideko; Wang, Amy; Zhang, Luoping; Zeise, Lauren; Fielden, Mark.

In: Cancer Epidemiology Biomarkers & Prevention, Vol. 29, No. 10, 10.2020, p. 1887-1903.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - The Key Characteristics of Carcinogens

T2 - Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them

AU - Smith, Martyn T

AU - Guyton, Kathryn Z

AU - Kleinstreuer, Nicole

AU - Borrel, Alexandre

AU - Cardenas, Andres

AU - Chiu, Weihsueh A

AU - Felsher, Dean W

AU - Gibbons, Catherine F

AU - Goodson, William H

AU - Houck, Keith A

AU - Kane, Agnes

AU - La Merrill, Michele A

AU - Lebrec, Herve

AU - Lowe, Leroy

AU - McHale, Cliona M

AU - Minocherhomji, Sheroy

AU - Rieswijk, Linda

AU - Sandy, Martha S

AU - Sone, Hideko

AU - Wang, Amy

AU - Zhang, Luoping

AU - Zeise, Lauren

AU - Fielden, Mark

PY - 2020/10

Y1 - 2020/10

KW - ARYL-HYDROCARBON RECEPTOR

KW - IN-SILICO PREDICTION

KW - GENOMIC INSTABILITY

KW - REPLICATION STRESS

KW - OXIDATIVE STRESS

KW - BREAST-CANCER

KW - DNA-DAMAGE

KW - INFLAMMATORY BIOMARKERS

KW - CHROMOSOMAL-ABERRATIONS

KW - REACTIVE METABOLITES

U2 - 10.1158/1055-9965.EPI-19-1346

DO - 10.1158/1055-9965.EPI-19-1346

M3 - Article

C2 - 32152214

VL - 29

SP - 1887

EP - 1903

JO - Cancer Epidemiology Biomarkers & Prevention

JF - Cancer Epidemiology Biomarkers & Prevention

SN - 1055-9965

IS - 10

ER -