The impact of metabolic control and tetrahydrobiopterin treatment on health related quality of life of patients with early-treated phenylketonuria: A PKU-COBESO study

Stephan C. J. Huijbregts, Annet M. Bosch, Quirine A. Simons, Rianne Jahja, Martijn C. G. J. Brouwers, Leo M. J. De Sonneville, Maaike C. De Vries, Floris C. Hofstede, Carla E. M. Hollak, Mirian C. H. Janssen, Janneke G. Langendonk, M. Estela Rubio-Gozalbo, Jaap J. Van der Meere, Ans T. Van der Ploeg, Francjan J. Van Spronsen

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)96-103
Number of pages8
JournalMolecular Genetics and Metabolism
Volume125
Issue number1-2
DOIs
Publication statusPublished - 1 Sep 2018

Keywords

  • Health-related quality of life
  • Phenylketonuria
  • Tetrahydrobiopterin
  • Metabolic control
  • Phenylalanine
  • WHITE-MATTER INTEGRITY
  • TERM-FOLLOW-UP
  • EXECUTIVE ABILITIES
  • MENTAL-HEALTH
  • ADULT PHENYLKETONURIA
  • AMINO-ACIDS
  • CHILDREN
  • PARENTS
  • INDIVIDUALS
  • SAPROPTERIN

Cite this

Huijbregts, S. C. J., Bosch, A. M., Simons, Q. A., Jahja, R., Brouwers, M. C. G. J., De Sonneville, L. M. J., De Vries, M. C., Hofstede, F. C., Hollak, C. E. M., Janssen, M. C. H., Langendonk, J. G., Rubio-Gozalbo, M. E., Van der Meere, J. J., Van der Ploeg, A. T., & Van Spronsen, F. J. (2018). The impact of metabolic control and tetrahydrobiopterin treatment on health related quality of life of patients with early-treated phenylketonuria: A PKU-COBESO study. Molecular Genetics and Metabolism, 125(1-2), 96-103. https://doi.org/10.1016/j.ymgme.2018.07.002