Abstract
Repeated single-point measurements of thoracic bioimpedance at a single (low) frequency are strongly related to fluid changes during hemodialysis. Extension to semi-continuous measurements may provide longitudinal details in the time pattern of the bioimpedance signal, and multi-frequency measurements may add in-depth information on the distribution between intra- and extracellular fluid. This study aimed to investigate the feasibility of semi-continuous multi-frequency thoracic bioimpedance measurements by a wearable device in hemodialysis patients. Therefore, thoracic bioimpedance was recorded semi-continuously (i.e., every ten minutes) at nine frequencies (8-160 kHz) in 68 patients during two consecutive hemodialysis sessions, complemented by a single-point measurement at home in-between both sessions. On average, the resistance signals increased during both hemodialysis sessions and decreased during the interdialytic interval. The increase during dialysis was larger at 8 kHz (? 32.6 O during session 1 and ? 10 O during session 2), compared to 160 kHz (? 29.5 O during session 1 and ? 5.1 O during session 2). Whereas the resistance at 8 kHz showed a linear time pattern, the evolution of the resistance at 160 kHz was significantly different ( < 0.0001). Measuring bioimpedance semi-continuously and w th a multi-frequency current is a major step forward in the understanding of fluid dynamics in hemodialysis patients. This study paves the road towards remote fluid monitoring.
Original language | English |
---|---|
Article number | 1890 |
Number of pages | 22 |
Journal | Sensors |
Volume | 24 |
Issue number | 6 |
DOIs | |
Publication status | Published - 15 Mar 2024 |
Keywords
- bioimpedance
- multi-frequency
- semi continuous
- thoracic
- wearable
- Humans
- Feasibility Studies
- Electric Impedance
- Renal Dialysis
- Extracellular Fluid
- Wearable Electronic Devices