The effect of embryonic genome imbalances on pregnancy

Masoud Zamani Esteki*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The prevalence of aneuploid cells in miscarried human embryos is higher than previously quoted. Genomic imbalances seem to be less tolerated in the embryoblast than the trophoblast, which indicates that allocation of aneuploid cells to the inner cell mass during blastocyst formation might have a detrimental effect on embryo development.
Original languageEnglish
Pages (from-to)3014-3015
Number of pages2
JournalNature Medicine
Volume29
Issue number12
DOIs
Publication statusPublished - Dec 2023

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