The DizzyQuest: relation between self-reported hearing loss, tinnitus and objective hearing thresholds in patients with Meniere's disease

E.C. Martin, R. Verkaik, J.J.A. Stultiens, M.R. van de Berg*, A.M.L. Janssen, C. Leue, P. Delespaul, F. Peeters, J. Widdershoven, A. Erdkamp, S.C.F. van de Weijer, H. Blom, A. Zwergal, E. Grill, N. Guinand, A. Perez-Fornos, D. Tse, R. van de Berg*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Background Combining a mobile application-based vestibular diary called the DizzyQuest and an iPad-based hearing test enables evaluation of the relationship between experienced neuro-otological symptoms and hearing thresholds in daily life setting. The aim was to investigate the relationship between self-reported hearing symptoms and hearing thresholds in patients with Meniere's disease (MD), using the DizzyQuest and the iPad-based hearing test simultaneously. Methods The DizzyQuest was administered for 3 weeks in 21 patients. Using the experience-sampling-method (ESM), it assessed hearing loss and tinnitus severity for both ears separately. Each day after the DizzyQuest, an iPad-based hearing test was used to measure hearing thresholds. A mixed model regression analysis was performed to investigate relationships between hearing thresholds and self-reported hearing loss and tinnitus severity. Results Fifteen patients were included. Overall, pure-tone averages (PTAs) were not correlated with self-reported hearing loss severity and tinnitus. Individual differences in PTA results between both ears did not significantly influence the difference in self-reported hearing loss severity between both ears. Self-reported hearing loss and tinnitus scores were significantly higher in ears that corresponded with audiometric criteria of MD (p < 0.001). Self-reported tinnitus severity significantly increased with self-reported hearing loss severity in affected (p = 0.011) and unaffected ears (p < 0.001). Conclusion Combining the DizzyQuest and iPad-based hearing test, facilitated assessment of self-reported hearing loss and tinnitus severity and their relationship with hearing thresholds, in a daily life setting. This study illustrated the importance of investigating neuro-otological symptoms at an individual level, using multiple measurements. ESM strategies like the DizzyQuest should therefore be considered in neuro-otological research.
Original languageEnglish
Pages (from-to)5239-5248
Number of pages10
JournalJournal of Neurology
Issue number10
Early online date11 Dec 2021
Publication statusPublished - Oct 2022


  • DizzyQuest
  • Meniere's disease
  • Tinnitus
  • Hearing loss
  • Audiometry
  • Experience sampling

Cite this