Task-relevant and accessory items in working memory have opposite effects on activity in extrastriate cortex

J.C. Peters, P.R. Roelfsema, R. Goebel

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Abstract

During visual search, the working memory (WM) representation of the search target guides attention to matching items in the visual scene. However, we can hold multiple items in WM. Do all these items guide attention at the same time? Using a new functional magnetic resonance imaging visual search paradigm, we found that items in WM can attain two different states that influence activity in extrastriate visual cortex in opposite directions: whereas the target item in WM enhanced processing of matching visual input, other "accessory" items in memory suppressed activity. These results imply that the representation of task-relevant and (currently) task-irrelevant representations in WM differs, revealing new insights into the organization of human visual WM. The suppressive influence of irrelevant WM items may complement the attention-guiding influence of task-relevant WM items, helping us to focus on task-relevant information without getting distracted by irrelevant memory content.
Original languageEnglish
Pages (from-to)17003-17011
Number of pages9
JournalJournal of Neuroscience
Volume32
Issue number47
DOIs
Publication statusPublished - 21 Nov 2012

Keywords

  • SHORT-TERM-MEMORY
  • INFERIOR TEMPORAL CORTEX
  • PRIMATE PREFRONTAL CORTEX
  • VISUAL-SEARCH
  • SELECTIVE ATTENTION
  • NEURAL MECHANISMS
  • INFORMATION
  • REPRESENTATION
  • OBJECTS
  • BRAIN

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