Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: A new concept of dual targeting drugs

Ludwig Dubois*, Sarah G. J. A. Peeters, Simon J. A. van Kuijk, Ala Yaromina, Natasja G. Lieuwes, Ruchi Saraya, Rianne Biemans, Marouan Rami, Nanda Kumar Parvathaneni, Daniela Vullo, Marc Vooijs, Claudiu T. Supuran, Jean-Yves Winum, Philippe Lambin

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

59 Citations (Web of Science)
Original languageEnglish
Pages (from-to)523-528
JournalRadiotherapy and Oncology
Issue number3
Publication statusPublished - Sep 2013


  • Carbonic anhydrase IX (CAIX)
  • Dual targeting
  • Sulfamide
  • 5-Nitroimidazole
  • Radiotherapy

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