TY - JOUR
T1 - Surgical outcomes of laparoscopic and open resection of benign liver tumours in the Netherlands
T2 - a nationwide analysis
AU - Elfrink, Arthur K. E.
AU - Haring, Martijn P. D.
AU - de Meijer, Vincent E.
AU - Ijzermans, Jan N. M.
AU - Swijnenburg, Rutger-Jan
AU - Braat, Andries E.
AU - Erdmann, Joris I.
AU - Terkivatan, Turkan
AU - te Riele, Wouter W.
AU - van den Boezem, Peter B.
AU - Coolsen, Marielle M. E.
AU - Leclercq, Wouter K. G.
AU - Lips, Daan J.
AU - de Wilde, Roeland F.
AU - Kok, Niels F. M.
AU - Grunhagen, Dirk J.
AU - Klaase, Joost M.
AU - Dutch Hepato Biliary Audit Group
PY - 2021/8
Y1 - 2021/8
N2 - Background: Data on surgical outcomes of laparoscopic liver resection (LLR) versus open liver resection (OLR) of benign liver tumour (BLT) are scarce. This study aimed to provide a nationwide overview of postoperative outcomes after LLR and OLR of BLT. Methods: This was a nationwide retrospective study including all patients who underwent liver resection for hepatocellular adenoma, haemangioma and focal nodular hyperplasia in the Netherlands from 2014 to 2019. Propensity score matching (PSM) was applied to compare 30-day overall and major morbidity and 30-day mortality after OLR and LLR. Results: In total, 415 patients underwent BLT resection of whom 230 (55.4%) underwent LLR. PSM for OLR and LLR resulted in 250 matched patients. Median (IQR) length of stay was shorter after LLR than OLR (4 versus 6 days, 5.0-8.0, p < 0.001). Postoperative 30-day overall morbidity was lower after LLR than OLR (12.0% vs. 22.4%, p = 0.043). LLR was associated with reduced 30-day overall morbidity in multivariable analysis (aOR:0.46, CI:0.22-0.95, p = 0.043). Both 30-day major morbidity and 30-day mortality were not different. Conclusions: LLR for BLT is associated with shorter hospital stay and reduced overall morbidity and is preferred if technically feasible.
AB - Background: Data on surgical outcomes of laparoscopic liver resection (LLR) versus open liver resection (OLR) of benign liver tumour (BLT) are scarce. This study aimed to provide a nationwide overview of postoperative outcomes after LLR and OLR of BLT. Methods: This was a nationwide retrospective study including all patients who underwent liver resection for hepatocellular adenoma, haemangioma and focal nodular hyperplasia in the Netherlands from 2014 to 2019. Propensity score matching (PSM) was applied to compare 30-day overall and major morbidity and 30-day mortality after OLR and LLR. Results: In total, 415 patients underwent BLT resection of whom 230 (55.4%) underwent LLR. PSM for OLR and LLR resulted in 250 matched patients. Median (IQR) length of stay was shorter after LLR than OLR (4 versus 6 days, 5.0-8.0, p < 0.001). Postoperative 30-day overall morbidity was lower after LLR than OLR (12.0% vs. 22.4%, p = 0.043). LLR was associated with reduced 30-day overall morbidity in multivariable analysis (aOR:0.46, CI:0.22-0.95, p = 0.043). Both 30-day major morbidity and 30-day mortality were not different. Conclusions: LLR for BLT is associated with shorter hospital stay and reduced overall morbidity and is preferred if technically feasible.
KW - MALIGNANT-TRANSFORMATION
KW - HEPATOCELLULAR ADENOMA
KW - HEPATIC-TUMORS
KW - TERM OUTCOMES
KW - MANAGEMENT
KW - SURGERY
KW - LESIONS
KW - TRENDS
U2 - 10.1016/j.hpb.2020.12.003
DO - 10.1016/j.hpb.2020.12.003
M3 - Article
C2 - 33478819
SN - 1365-182X
VL - 23
SP - 1230
EP - 1243
JO - HPB
JF - HPB
IS - 8
ER -