Surface characterization of polymethacrylate coated biochips with water-in-air contact angle analysis

Samira Hosseini, Ivan Djordjevic, Leo H. Koole, Victor H. Perez-Gonzalez, Roberto C. Gallo-Villanueva, Sergio O. Martinez-Chapa

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

Abstract

In this paper, the synthesis and development of the polymeric biochips have been described in detail. Different compositions of the copolymer poly methyl methacrylate-co-methacrylic acid poly(MMA-co-MAA) have been synthesized through free-radical polymerization reaction. Biochips aimed for virus detection have been developed by coating silicon wafers by using spin coating technique. A thin layer of coatings on the surface of biochips has been produced from polymer solution of different copolymer compositions. A detailed surface analysis of the biochips was conducted by using of water-in-air contact angle measurement in order to assess the wettability of the coated biochips. Hydrophilicity of the surfaces was further studied by conducting measurements in different pH of the solutions, which has revealed direct correlation between wettability of the analyzed platforms and the presence of carboxyl (-COOH) functional groups on the surface.
Original languageEnglish
Title of host publicationMaterials Engineering and Sciences Division 2016 - Core Programming Area at the 2016 AIChE Annual Meeting
PublisherAmerican Institute of Chemical Engineers
Pages991-995
Number of pages5
Volume2
ISBN (Electronic)9781510834408
Publication statusPublished - 1 Jan 2016
EventMaterials Engineering and Sciences Division 2016 - Core Programming Area at the 2016 AIChE Annual Meeting - San Francisco, United States
Duration: 13 Nov 201618 Nov 2016

Conference

ConferenceMaterials Engineering and Sciences Division 2016 - Core Programming Area at the 2016 AIChE Annual Meeting
Country/TerritoryUnited States
CitySan Francisco
Period13/11/1618/11/16

Keywords

  • Hydrophilicity
  • Hydrophobicity
  • Surface functional groups
  • Surface property
  • Water-in-air contact angle

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