Stigmatic imaging of secondary ions in MeV-SIMS spectrometry by linear Time-of-Flight mass spectrometer and the TimePix detector

Bastjan Jencic*, Luka Sepec, Primoz Vavpetic, Mitja Kelemen, Zdravko Rupnik, Matjaz Vencelj, Katarina Vogel-Mikus, Nina Ogrinc Potocnik, Shane R. Ellis, Ron Heeren, Primoz Pelicon

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Secondary ion mass spectrometry (SIMS), based on primary ions within the MeV energy domain, also known as MeV-SIMS, is a subject of increasing scientific interest. The main drive for the interest in the development of MeV-SIMS is the ability to desorb high yields of large non-fragmented organic molecular ions from the sample surface. This makes MeV-SIMS particulary useful in imaging of biological tissues.
Imaging methods based on scanning a focused primary ion beam are associated with demanding focusing of the heavy energetic ions. As an alternative, stigmatic imaging mode has been studied here, applying point-to-point imaging characteristics of secondary ions in the linear Time-Of-Flight mass spectrometer. In stigmatic imaging approaches, spatial resolution is independent of the focussed spot size of the ionising primary ion beam, but instead dependant on the ability of the ion optics to project an image of the ion distributions removed from the surface onto a position sensitive ion detector.
Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalNuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms
Volume452
DOIs
Publication statusPublished - 1 Aug 2019

Keywords

  • MeV-SIMS
  • Stigmatic imaging
  • Time-of-Flight
  • TISSUE
  • DESORPTION
  • LASER

Cite this

Jencic, Bastjan ; Sepec, Luka ; Vavpetic, Primoz ; Kelemen, Mitja ; Rupnik, Zdravko ; Vencelj, Matjaz ; Vogel-Mikus, Katarina ; Potocnik, Nina Ogrinc ; Ellis, Shane R. ; Heeren, Ron ; Pelicon, Primoz. / Stigmatic imaging of secondary ions in MeV-SIMS spectrometry by linear Time-of-Flight mass spectrometer and the TimePix detector. In: Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms. 2019 ; Vol. 452. pp. 1-6.
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title = "Stigmatic imaging of secondary ions in MeV-SIMS spectrometry by linear Time-of-Flight mass spectrometer and the TimePix detector",
abstract = "Secondary ion mass spectrometry (SIMS), based on primary ions within the MeV energy domain, also known as MeV-SIMS, is a subject of increasing scientific interest. The main drive for the interest in the development of MeV-SIMS is the ability to desorb high yields of large non-fragmented organic molecular ions from the sample surface. This makes MeV-SIMS particulary useful in imaging of biological tissues.Imaging methods based on scanning a focused primary ion beam are associated with demanding focusing of the heavy energetic ions. As an alternative, stigmatic imaging mode has been studied here, applying point-to-point imaging characteristics of secondary ions in the linear Time-Of-Flight mass spectrometer. In stigmatic imaging approaches, spatial resolution is independent of the focussed spot size of the ionising primary ion beam, but instead dependant on the ability of the ion optics to project an image of the ion distributions removed from the surface onto a position sensitive ion detector.",
keywords = "MeV-SIMS, Stigmatic imaging, Time-of-Flight, TISSUE, DESORPTION, LASER",
author = "Bastjan Jencic and Luka Sepec and Primoz Vavpetic and Mitja Kelemen and Zdravko Rupnik and Matjaz Vencelj and Katarina Vogel-Mikus and Potocnik, {Nina Ogrinc} and Ellis, {Shane R.} and Ron Heeren and Primoz Pelicon",
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Stigmatic imaging of secondary ions in MeV-SIMS spectrometry by linear Time-of-Flight mass spectrometer and the TimePix detector. / Jencic, Bastjan; Sepec, Luka; Vavpetic, Primoz; Kelemen, Mitja; Rupnik, Zdravko; Vencelj, Matjaz; Vogel-Mikus, Katarina; Potocnik, Nina Ogrinc; Ellis, Shane R.; Heeren, Ron; Pelicon, Primoz.

In: Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms, Vol. 452, 01.08.2019, p. 1-6.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Stigmatic imaging of secondary ions in MeV-SIMS spectrometry by linear Time-of-Flight mass spectrometer and the TimePix detector

AU - Jencic, Bastjan

AU - Sepec, Luka

AU - Vavpetic, Primoz

AU - Kelemen, Mitja

AU - Rupnik, Zdravko

AU - Vencelj, Matjaz

AU - Vogel-Mikus, Katarina

AU - Potocnik, Nina Ogrinc

AU - Ellis, Shane R.

AU - Heeren, Ron

AU - Pelicon, Primoz

PY - 2019/8/1

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N2 - Secondary ion mass spectrometry (SIMS), based on primary ions within the MeV energy domain, also known as MeV-SIMS, is a subject of increasing scientific interest. The main drive for the interest in the development of MeV-SIMS is the ability to desorb high yields of large non-fragmented organic molecular ions from the sample surface. This makes MeV-SIMS particulary useful in imaging of biological tissues.Imaging methods based on scanning a focused primary ion beam are associated with demanding focusing of the heavy energetic ions. As an alternative, stigmatic imaging mode has been studied here, applying point-to-point imaging characteristics of secondary ions in the linear Time-Of-Flight mass spectrometer. In stigmatic imaging approaches, spatial resolution is independent of the focussed spot size of the ionising primary ion beam, but instead dependant on the ability of the ion optics to project an image of the ion distributions removed from the surface onto a position sensitive ion detector.

AB - Secondary ion mass spectrometry (SIMS), based on primary ions within the MeV energy domain, also known as MeV-SIMS, is a subject of increasing scientific interest. The main drive for the interest in the development of MeV-SIMS is the ability to desorb high yields of large non-fragmented organic molecular ions from the sample surface. This makes MeV-SIMS particulary useful in imaging of biological tissues.Imaging methods based on scanning a focused primary ion beam are associated with demanding focusing of the heavy energetic ions. As an alternative, stigmatic imaging mode has been studied here, applying point-to-point imaging characteristics of secondary ions in the linear Time-Of-Flight mass spectrometer. In stigmatic imaging approaches, spatial resolution is independent of the focussed spot size of the ionising primary ion beam, but instead dependant on the ability of the ion optics to project an image of the ion distributions removed from the surface onto a position sensitive ion detector.

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