Spatial heterogeneity of nanomedicine investigated by multiscale imaging of the drug, the nanoparticle and the tumour environment

J.S. de Maar, A.M. Sofias, T.P. Siegel, R.J. Vreeken, C. Moonen, C. Bos, R. Deckers

Research output: Contribution to journalReview articlepeer-review

Original languageEnglish
Pages (from-to)1884-1909
Number of pages26
JournalTheranostics
Volume10
Issue number4
DOIs
Publication statusPublished - 1 Jan 2020

Keywords

  • breast-cancer
  • clinical imaging
  • contrast-enhanced ultrasound
  • drug distribution
  • emission computed-tomography
  • in-vivo
  • intratumoral distribution
  • intravital microscopy
  • liposomal doxorubicin
  • mass spectrometry imaging.
  • mass-spectrometry
  • nanomedicine
  • optical imaging
  • photoacoustic tomography
  • therapeutic-efficacy
  • CONTRAST-ENHANCED ULTRASOUND
  • MASS-SPECTROMETRY
  • BREAST-CANCER
  • INTRATUMORAL DISTRIBUTION
  • LIPOSOMAL DOXORUBICIN
  • THERAPEUTIC-EFFICACY
  • Clinical Imaging
  • Nanomedicine
  • Drug distribution
  • Optical imaging
  • Mass Spectrometry Imaging.
  • EMISSION COMPUTED-TOMOGRAPHY
  • IN-VIVO
  • PHOTOACOUSTIC TOMOGRAPHY
  • INTRAVITAL MICROSCOPY

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