Somatic mutations in neurons during aging and neurodegeneration

Bert M. Verheijen*, Marc Vermulst, Fred W. van Leeuwen

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Pages (from-to)811-826
Number of pages16
JournalActa Neuropathologica
Volume135
Issue number6
DOIs
Publication statusPublished - 1 Jun 2018

Keywords

  • Somatic mutations
  • Genome integrity
  • Somatic brain mosaicism
  • Neuronal development
  • Aging
  • Neurological disorders
  • Neurodegeneration
  • HOMOZYGOUS BRATTLEBORO RAT
  • SOLITARY MAGNOCELLULAR NEURONS
  • CEREBRAL AMYLOID ANGIOPATHY
  • ALZHEIMERS-DISEASE PATIENTS
  • FOCAL CORTICAL DYSPLASIA
  • HUMAN BRAIN-DEVELOPMENT
  • COPY-NUMBER VARIATION
  • DOUBLE-STRAND BREAKS
  • SINGLE-CELL
  • IN-VIVO

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