Somatic mutations in neurons during aging and neurodegeneration

Bert M. Verheijen; Marc Vermulst; Fred W. van Leeuwen

doi:10.1007/s00401-018-1850-y

Somatic mutations in neurons during aging and neurodegeneration

Bert M. Verheijen^*, Marc Vermulst, Fred W. van Leeuwen

^*Corresponding author for this work

MHeNs - Neuroscience

Research output: Contribution to journal › Review article › Academic › peer-review

Original language	English
Pages (from-to)	811-826
Number of pages	16
Journal	Acta Neuropathologica
Volume	135
Issue number	6
DOIs	https://doi.org/10.1007/s00401-018-1850-y
Publication status	Published - 1 Jun 2018

Keywords

Somatic mutations
Genome integrity
Somatic brain mosaicism
Neuronal development
Aging
Neurological disorders
Neurodegeneration
HOMOZYGOUS BRATTLEBORO RAT
SOLITARY MAGNOCELLULAR NEURONS
CEREBRAL AMYLOID ANGIOPATHY
ALZHEIMERS-DISEASE PATIENTS
FOCAL CORTICAL DYSPLASIA
HUMAN BRAIN-DEVELOPMENT
COPY-NUMBER VARIATION
DOUBLE-STRAND BREAKS
SINGLE-CELL
IN-VIVO

Access to Document

10.1007/s00401-018-1850-y

https://link.springer.com/content/pdf/10.1007%2Fs00401-018-1850-y.pdf

Cite this

@article{3b8301237da04ac9ad5ba8ea4d24ecea,

title = "Somatic mutations in neurons during aging and neurodegeneration",

keywords = "Somatic mutations, Genome integrity, Somatic brain mosaicism, Neuronal development, Aging, Neurological disorders, Neurodegeneration, HOMOZYGOUS BRATTLEBORO RAT, SOLITARY MAGNOCELLULAR NEURONS, CEREBRAL AMYLOID ANGIOPATHY, ALZHEIMERS-DISEASE PATIENTS, FOCAL CORTICAL DYSPLASIA, HUMAN BRAIN-DEVELOPMENT, COPY-NUMBER VARIATION, DOUBLE-STRAND BREAKS, SINGLE-CELL, IN-VIVO",

author = "Verheijen, {Bert M.} and Marc Vermulst and {van Leeuwen}, {Fred W.}",

year = "2018",

month = jun,

day = "1",

doi = "10.1007/s00401-018-1850-y",

language = "English",

volume = "135",

pages = "811--826",

journal = "Acta Neuropathologica",

issn = "0001-6322",

publisher = "Springer, Cham",

number = "6",

}

TY - JOUR

T1 - Somatic mutations in neurons during aging and neurodegeneration

AU - Verheijen, Bert M.

AU - Vermulst, Marc

AU - van Leeuwen, Fred W.

PY - 2018/6/1

Y1 - 2018/6/1

KW - Somatic mutations

KW - Genome integrity

KW - Somatic brain mosaicism

KW - Neuronal development

KW - Aging

KW - Neurological disorders

KW - Neurodegeneration

KW - HOMOZYGOUS BRATTLEBORO RAT

KW - SOLITARY MAGNOCELLULAR NEURONS

KW - CEREBRAL AMYLOID ANGIOPATHY

KW - ALZHEIMERS-DISEASE PATIENTS

KW - FOCAL CORTICAL DYSPLASIA

KW - HUMAN BRAIN-DEVELOPMENT

KW - COPY-NUMBER VARIATION

KW - DOUBLE-STRAND BREAKS

KW - SINGLE-CELL

KW - IN-VIVO

U2 - 10.1007/s00401-018-1850-y

DO - 10.1007/s00401-018-1850-y

M3 - Review article

C2 - 29705908

VL - 135

SP - 811

EP - 826

JO - Acta Neuropathologica

JF - Acta Neuropathologica

SN - 0001-6322

IS - 6

ER -