Software development for hepatopulmonary shunt estimation by gamma camera method in transarterial radioembolization

Ashish Kumar Jha, Sneha Mithun, Ameya Puranik, Nilendu C Purandare, Sneha Shah, Archi Agrawal, Suyash S Kulkarni, Nitin Shetty, Venkatesh Rangarajan*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Trans-arterial radioembolization (TARE) is an established treatment for inoperable hepatocellular carcinoma and liver metastases from Carcinoma of gastrointestinal tract. Radiation-induced toxicity to the lung parenchyma is the dose-limiting factor in TARE. Pretreatment hepatopulmonary shunt (HPS) is estimated by gamma camera method by transarterial administration of 370MBq 99mTc macro aggregated albumin. We have developed HPS software on XELERIS-1.123 workstation, GE medical systems, Milwaukee, USA, for accurate calculation of HPS. This software has also been tested on a higher version of XELERIS workstation, and it has been found to work well in all versions.

Original languageEnglish
Pages (from-to)366-372
Number of pages7
JournalWorld Journal of Nuclear Medicine
Issue number4
Publication statusPublished - 2019
Externally publishedYes


  • Hepatopulmonary shunt
  • transarterial radioembolization
  • Y-90 microspheres

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