Software development for hepatopulmonary shunt estimation by gamma camera method in transarterial radioembolization

Ashish Kumar Jha; Sneha Mithun; Ameya Puranik; Nilendu C Purandare; Sneha Shah; Archi Agrawal; Suyash S Kulkarni; Nitin Shetty; Venkatesh Rangarajan

doi:10.4103/wjnm.WJNM_115_18

Software development for hepatopulmonary shunt estimation by gamma camera method in transarterial radioembolization

Ashish Kumar Jha, Sneha Mithun, Ameya Puranik, Nilendu C Purandare, Sneha Shah, Archi Agrawal, Suyash S Kulkarni, Nitin Shetty, Venkatesh Rangarajan^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Trans-arterial radioembolization (TARE) is an established treatment for inoperable hepatocellular carcinoma and liver metastases from Carcinoma of gastrointestinal tract. Radiation-induced toxicity to the lung parenchyma is the dose-limiting factor in TARE. Pretreatment hepatopulmonary shunt (HPS) is estimated by gamma camera method by transarterial administration of 370MBq 99mTc macro aggregated albumin. We have developed HPS software on XELERIS-1.123 workstation, GE medical systems, Milwaukee, USA, for accurate calculation of HPS. This software has also been tested on a higher version of XELERIS workstation, and it has been found to work well in all versions.

Original language	English
Pages (from-to)	366-372
Number of pages	7
Journal	World Journal of Nuclear Medicine
Volume	18
Issue number	4
DOIs	https://doi.org/10.4103/wjnm.WJNM_115_18
Publication status	Published - 2019
Externally published	Yes

Keywords

Hepatopulmonary shunt
transarterial radioembolization
Y-90 microspheres

Access to Document

10.4103/wjnm.WJNM_115_18

Full TextFinal published version, 1.57 MBLicence: Taverne

Cite this

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title = "Software development for hepatopulmonary shunt estimation by gamma camera method in transarterial radioembolization",

abstract = "Trans-arterial radioembolization (TARE) is an established treatment for inoperable hepatocellular carcinoma and liver metastases from Carcinoma of gastrointestinal tract. Radiation-induced toxicity to the lung parenchyma is the dose-limiting factor in TARE. Pretreatment hepatopulmonary shunt (HPS) is estimated by gamma camera method by transarterial administration of 370MBq 99mTc macro aggregated albumin. We have developed HPS software on XELERIS-1.123 workstation, GE medical systems, Milwaukee, USA, for accurate calculation of HPS. This software has also been tested on a higher version of XELERIS workstation, and it has been found to work well in all versions.",

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doi = "10.4103/wjnm.WJNM_115_18",

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T1 - Software development for hepatopulmonary shunt estimation by gamma camera method in transarterial radioembolization

AU - Jha, Ashish Kumar

AU - Mithun, Sneha

AU - Puranik, Ameya

AU - Purandare, Nilendu C

AU - Shah, Sneha

AU - Agrawal, Archi

AU - Kulkarni, Suyash S

AU - Shetty, Nitin

AU - Rangarajan, Venkatesh

PY - 2019

Y1 - 2019

N2 - Trans-arterial radioembolization (TARE) is an established treatment for inoperable hepatocellular carcinoma and liver metastases from Carcinoma of gastrointestinal tract. Radiation-induced toxicity to the lung parenchyma is the dose-limiting factor in TARE. Pretreatment hepatopulmonary shunt (HPS) is estimated by gamma camera method by transarterial administration of 370MBq 99mTc macro aggregated albumin. We have developed HPS software on XELERIS-1.123 workstation, GE medical systems, Milwaukee, USA, for accurate calculation of HPS. This software has also been tested on a higher version of XELERIS workstation, and it has been found to work well in all versions.

AB - Trans-arterial radioembolization (TARE) is an established treatment for inoperable hepatocellular carcinoma and liver metastases from Carcinoma of gastrointestinal tract. Radiation-induced toxicity to the lung parenchyma is the dose-limiting factor in TARE. Pretreatment hepatopulmonary shunt (HPS) is estimated by gamma camera method by transarterial administration of 370MBq 99mTc macro aggregated albumin. We have developed HPS software on XELERIS-1.123 workstation, GE medical systems, Milwaukee, USA, for accurate calculation of HPS. This software has also been tested on a higher version of XELERIS workstation, and it has been found to work well in all versions.

KW - Hepatopulmonary shunt

KW - transarterial radioembolization

KW - Y-90 microspheres

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