Small Fiber Neuropathy: A Clinical and Practical Approach

M. Geerts; J.G.J. Hoeijmakers; C.M.L. Gorissen-Brouwers; C.G. Faber; I.S.J. Merkies

doi:10.1016/j.nurpra.2023.104547

Small Fiber Neuropathy: A Clinical and Practical Approach

M. Geerts^*, J.G.J. Hoeijmakers, C.M.L. Gorissen-Brouwers, C.G. Faber, I.S.J. Merkies

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Small fiber neuropathy (SFN) is a peripheral nerve condition causing neuropathic pain and autonomic complaints. Skin biopsy is an important diagnostic tool for diagnosing SFN. SFN is associated with conditions like diabetes mellitus and autoimmune diseases, but in 53% of the patients, the etiology remains unknown. Treating the underlying condition is the first-line treatment, but most patients will also need symptomatic treatment based on the biopsychosocial model. SFN can be managed by several health care professionals, including nurse practitioners, neurologists, pain specialists, and physiatrists. This article provides evidencebased information on the diagnostics of SFN and offers guidance for interdisciplinary treatment.(c) 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Original language	English
Article number	104547
Number of pages	9
Journal	Journal for Nurse Practitioners
Volume	19
Issue number	4
DOIs	https://doi.org/10.1016/j.nurpra.2023.104547
Publication status	Published - 1 Apr 2023

Keywords

diagnostic tests
interdisciplinary treatment
neuropathic pain treatment
nurse practitioners
small fiber neuropathy
QUALITY-OF-LIFE
SODIUM-CHANNELS
LARGE COHORT
PAIN
FUTURE

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Cite this

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title = "Small Fiber Neuropathy: A Clinical and Practical Approach",

abstract = "Small fiber neuropathy (SFN) is a peripheral nerve condition causing neuropathic pain and autonomic complaints. Skin biopsy is an important diagnostic tool for diagnosing SFN. SFN is associated with conditions like diabetes mellitus and autoimmune diseases, but in 53% of the patients, the etiology remains unknown. Treating the underlying condition is the first-line treatment, but most patients will also need symptomatic treatment based on the biopsychosocial model. SFN can be managed by several health care professionals, including nurse practitioners, neurologists, pain specialists, and physiatrists. This article provides evidencebased information on the diagnostics of SFN and offers guidance for interdisciplinary treatment.(c) 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).",

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AU - Hoeijmakers, J.G.J.

AU - Gorissen-Brouwers, C.M.L.

AU - Faber, C.G.

AU - Merkies, I.S.J.

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N2 - Small fiber neuropathy (SFN) is a peripheral nerve condition causing neuropathic pain and autonomic complaints. Skin biopsy is an important diagnostic tool for diagnosing SFN. SFN is associated with conditions like diabetes mellitus and autoimmune diseases, but in 53% of the patients, the etiology remains unknown. Treating the underlying condition is the first-line treatment, but most patients will also need symptomatic treatment based on the biopsychosocial model. SFN can be managed by several health care professionals, including nurse practitioners, neurologists, pain specialists, and physiatrists. This article provides evidencebased information on the diagnostics of SFN and offers guidance for interdisciplinary treatment.(c) 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

AB - Small fiber neuropathy (SFN) is a peripheral nerve condition causing neuropathic pain and autonomic complaints. Skin biopsy is an important diagnostic tool for diagnosing SFN. SFN is associated with conditions like diabetes mellitus and autoimmune diseases, but in 53% of the patients, the etiology remains unknown. Treating the underlying condition is the first-line treatment, but most patients will also need symptomatic treatment based on the biopsychosocial model. SFN can be managed by several health care professionals, including nurse practitioners, neurologists, pain specialists, and physiatrists. This article provides evidencebased information on the diagnostics of SFN and offers guidance for interdisciplinary treatment.(c) 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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