Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488

Francesco Marchetti; Marilyn Aardema; Carol Beevers; Jan van Benthem; George R. Douglas; Roger Godschalk; Carole L. Yauk; Robert Young; Andrew Williams

doi:10.1016/j.mrgentox.2018.05.020

Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488

Francesco Marchetti^*, Marilyn Aardema, Carol Beevers, Jan van Benthem, George R. Douglas, Roger Godschalk, Carole L. Yauk, Robert Young, Andrew Williams

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	19-28
Number of pages	10
Journal	Mutation Research-Genetic Toxicology and Environmental Mutagenesis
Volume	832
DOIs	https://doi.org/10.1016/j.mrgentox.2018.05.020
Publication status	Published - Aug 2018

Keywords

Mutations
Germ cells
Transgene
Test guideline
Rodent
SPERMATOGONIAL STEM-CELLS
GERM-CELLS
LIFE-HISTORY
ADULT RATS
CYCLE
PROLIFERATION
APOPTOSIS
SPERMATOCYTES
MUTAGENICITY
POPULATION

Cite this

Marchetti, F., Aardema, M., Beevers, C., van Benthem, J., Douglas, G. R., Godschalk, R., Yauk, C. L., Young, R., & Williams, A. (2018). Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488. Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 832, 19-28. https://doi.org/10.1016/j.mrgentox.2018.05.020

Marchetti, Francesco ; Aardema, Marilyn ; Beevers, Carol ; van Benthem, Jan ; Douglas, George R. ; Godschalk, Roger ; Yauk, Carole L. ; Young, Robert ; Williams, Andrew. / Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488. In: Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 2018 ; Vol. 832. pp. 19-28.

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title = "Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488",

keywords = "Mutations, Germ cells, Transgene, Test guideline, Rodent, SPERMATOGONIAL STEM-CELLS, GERM-CELLS, LIFE-HISTORY, ADULT RATS, CYCLE, PROLIFERATION, APOPTOSIS, SPERMATOCYTES, MUTAGENICITY, POPULATION",

author = "Francesco Marchetti and Marilyn Aardema and Carol Beevers and {van Benthem}, Jan and Douglas, {George R.} and Roger Godschalk and Yauk, {Carole L.} and Robert Young and Andrew Williams",

year = "2018",

month = aug

doi = "10.1016/j.mrgentox.2018.05.020",

language = "English",

volume = "832",

pages = "19--28",

journal = "Mutation Research-Genetic Toxicology and Environmental Mutagenesis",

issn = "1383-5718",

publisher = "Elsevier",

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Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488. / Marchetti, Francesco; Aardema, Marilyn; Beevers, Carol; van Benthem, Jan; Douglas, George R.; Godschalk, Roger; Yauk, Carole L.; Young, Robert; Williams, Andrew.

In: Mutation Research-Genetic Toxicology and Environmental Mutagenesis, Vol. 832, 08.2018, p. 19-28.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488

AU - Marchetti, Francesco

AU - Aardema, Marilyn

AU - Beevers, Carol

AU - van Benthem, Jan

AU - Douglas, George R.

AU - Godschalk, Roger

AU - Yauk, Carole L.

AU - Young, Robert

AU - Williams, Andrew

PY - 2018/8

Y1 - 2018/8

KW - Mutations

KW - Germ cells

KW - Transgene

KW - Test guideline

KW - Rodent

KW - SPERMATOGONIAL STEM-CELLS

KW - GERM-CELLS

KW - LIFE-HISTORY

KW - ADULT RATS

KW - CYCLE

KW - PROLIFERATION

KW - APOPTOSIS

KW - SPERMATOCYTES

KW - MUTAGENICITY

KW - POPULATION

U2 - 10.1016/j.mrgentox.2018.05.020

DO - 10.1016/j.mrgentox.2018.05.020

M3 - Article

VL - 832

SP - 19

EP - 28

JO - Mutation Research-Genetic Toxicology and Environmental Mutagenesis

JF - Mutation Research-Genetic Toxicology and Environmental Mutagenesis

SN - 1383-5718

ER -

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10.1016/j.mrgentox.2018.05.020Licence: CC BY