Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488

Francesco Marchetti*, Marilyn Aardema, Carol Beevers, Jan van Benthem, George R. Douglas, Roger Godschalk, Carole L. Yauk, Robert Young, Andrew Williams

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)19-28
Number of pages10
JournalMutation Research-Genetic Toxicology and Environmental Mutagenesis
Volume832
DOIs
Publication statusPublished - Aug 2018

Keywords

  • Mutations
  • Germ cells
  • Transgene
  • Test guideline
  • Rodent
  • SPERMATOGONIAL STEM-CELLS
  • GERM-CELLS
  • LIFE-HISTORY
  • ADULT RATS
  • CYCLE
  • PROLIFERATION
  • APOPTOSIS
  • SPERMATOCYTES
  • MUTAGENICITY
  • POPULATION

Cite this

Marchetti, Francesco ; Aardema, Marilyn ; Beevers, Carol ; van Benthem, Jan ; Douglas, George R. ; Godschalk, Roger ; Yauk, Carole L. ; Young, Robert ; Williams, Andrew. / Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488. In: Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 2018 ; Vol. 832. pp. 19-28.
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title = "Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488",
keywords = "Mutations, Germ cells, Transgene, Test guideline, Rodent, SPERMATOGONIAL STEM-CELLS, GERM-CELLS, LIFE-HISTORY, ADULT RATS, CYCLE, PROLIFERATION, APOPTOSIS, SPERMATOCYTES, MUTAGENICITY, POPULATION",
author = "Francesco Marchetti and Marilyn Aardema and Carol Beevers and {van Benthem}, Jan and Douglas, {George R.} and Roger Godschalk and Yauk, {Carole L.} and Robert Young and Andrew Williams",
year = "2018",
month = "8",
doi = "10.1016/j.mrgentox.2018.05.020",
language = "English",
volume = "832",
pages = "19--28",
journal = "Mutation Research-Genetic Toxicology and Environmental Mutagenesis",
issn = "1383-5718",
publisher = "Elsevier",

}

Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488. / Marchetti, Francesco; Aardema, Marilyn; Beevers, Carol; van Benthem, Jan; Douglas, George R.; Godschalk, Roger; Yauk, Carole L.; Young, Robert; Williams, Andrew.

In: Mutation Research-Genetic Toxicology and Environmental Mutagenesis, Vol. 832, 08.2018, p. 19-28.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488

AU - Marchetti, Francesco

AU - Aardema, Marilyn

AU - Beevers, Carol

AU - van Benthem, Jan

AU - Douglas, George R.

AU - Godschalk, Roger

AU - Yauk, Carole L.

AU - Young, Robert

AU - Williams, Andrew

PY - 2018/8

Y1 - 2018/8

KW - Mutations

KW - Germ cells

KW - Transgene

KW - Test guideline

KW - Rodent

KW - SPERMATOGONIAL STEM-CELLS

KW - GERM-CELLS

KW - LIFE-HISTORY

KW - ADULT RATS

KW - CYCLE

KW - PROLIFERATION

KW - APOPTOSIS

KW - SPERMATOCYTES

KW - MUTAGENICITY

KW - POPULATION

U2 - 10.1016/j.mrgentox.2018.05.020

DO - 10.1016/j.mrgentox.2018.05.020

M3 - Article

VL - 832

SP - 19

EP - 28

JO - Mutation Research-Genetic Toxicology and Environmental Mutagenesis

JF - Mutation Research-Genetic Toxicology and Environmental Mutagenesis

SN - 1383-5718

ER -