TY - JOUR
T1 - Sense and non-sense of imaging in the era of organ preservation for rectal cancer
AU - Ou, Xinde
AU - van der Reijd, Denise J
AU - Lambregts, Doenja Mj
AU - Grotenhuis, Brechtje A
AU - van Triest, Baukelien
AU - Beets, Geerard L
AU - Beets-Tan, Regina Gh
AU - Maas, Monique
PY - 2023/9/26
Y1 - 2023/9/26
N2 - This review summarizes the current applications and benefits of imaging modalities for organ preservation in the treatment of rectal cancer. The concept of organ preservation in the treatment of rectal cancer has revolutionized the way rectal cancer is managed. Initially, organ preservation was limited to patients with locally advanced rectal cancer who needed neoadjuvant therapy to reduce tumor size before surgery and achieved complete response. However, neoadjuvant therapy is now increasingly utilized for smaller and less aggressive tumors to achieve primary organ preservation. Additionally, more intensive neoadjuvant strategies are employed to improve complete response rates and increase the chances of successful organ preservation. The selection of patients for organ preservation is a critical component of treatment, and imaging techniques such as digital rectal exam, endoscopy, and MRI are commonly used for this purpose. In this review, we provide an overview of what imaging modalities should be chosen and how they can aid in the selection and follow-up of patients undergoing organ-preserving strategies.
AB - This review summarizes the current applications and benefits of imaging modalities for organ preservation in the treatment of rectal cancer. The concept of organ preservation in the treatment of rectal cancer has revolutionized the way rectal cancer is managed. Initially, organ preservation was limited to patients with locally advanced rectal cancer who needed neoadjuvant therapy to reduce tumor size before surgery and achieved complete response. However, neoadjuvant therapy is now increasingly utilized for smaller and less aggressive tumors to achieve primary organ preservation. Additionally, more intensive neoadjuvant strategies are employed to improve complete response rates and increase the chances of successful organ preservation. The selection of patients for organ preservation is a critical component of treatment, and imaging techniques such as digital rectal exam, endoscopy, and MRI are commonly used for this purpose. In this review, we provide an overview of what imaging modalities should be chosen and how they can aid in the selection and follow-up of patients undergoing organ-preserving strategies.
U2 - 10.1259/bjr.20230318
DO - 10.1259/bjr.20230318
M3 - (Systematic) Review article
SN - 0007-1285
VL - 96
JO - British Journal of Radiology
JF - British Journal of Radiology
IS - 1151
M1 - 20230318
ER -