Sense and non-sense of imaging in the era of organ preservation for rectal cancer

Xinde Ou, Denise J van der Reijd, Doenja Mj Lambregts, Brechtje A Grotenhuis, Baukelien van Triest, Geerard L Beets, Regina Gh Beets-Tan, Monique Maas*

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

Abstract

This review summarizes the current applications and benefits of imaging modalities for organ preservation in the treatment of rectal cancer. The concept of organ preservation in the treatment of rectal cancer has revolutionized the way rectal cancer is managed. Initially, organ preservation was limited to patients with locally advanced rectal cancer who needed neoadjuvant therapy to reduce tumor size before surgery and achieved complete response. However, neoadjuvant therapy is now increasingly utilized for smaller and less aggressive tumors to achieve primary organ preservation. Additionally, more intensive neoadjuvant strategies are employed to improve complete response rates and increase the chances of successful organ preservation. The selection of patients for organ preservation is a critical component of treatment, and imaging techniques such as digital rectal exam, endoscopy, and MRI are commonly used for this purpose. In this review, we provide an overview of what imaging modalities should be chosen and how they can aid in the selection and follow-up of patients undergoing organ-preserving strategies.
Original languageEnglish
Article number20230318
JournalBritish Journal of Radiology
Volume96
Issue number1151
DOIs
Publication statusPublished - 26 Sept 2023

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