Abstract
PURPOSE OF REVIEW: After three decades of clinical research on repetitive transcranial magnetic stimulation (rTMS), major depressive disorder (MDD) has proven to be the primary field of application. MDD poses a major challenge for health systems worldwide, emphasizing the need for improving clinical efficacy of existing rTMS applications and promoting the development of novel evidence-based rTMS treatment approaches.
RECENT FINDINGS: Several promising new avenues have been proposed: novel stimulation patterns, targets, and coils; combinatory treatments and maintenance; and personalization and stratification of rTMS parameters, and treatment of subpopulations.
SUMMARY: This opinion review summarizes current knowledge in the field and addresses the future direction of rTMS treatment in MDD, facilitating the establishment of this clinical intervention method as a standard treatment option and continuing to improve response and remission rates, and take the necessary steps to personalize rTMS-based treatment approaches.
| Original language | English |
|---|---|
| Pages (from-to) | 409–415 |
| Number of pages | 7 |
| Journal | Current Opinion in Psychiatry |
| Volume | 32 |
| Issue number | 5 |
| Early online date | 27 May 2019 |
| DOIs | |
| Publication status | Published - Sep 2019 |
Keywords
- BIPOLAR DEPRESSION
- DEEP TMS
- DOUBLE-BLIND
- EFFICACY
- MAJOR DEPRESSION
- METAANALYSIS
- NETWORK
- RTMS
- TMS TREATMENT
- TREATMENT-RESISTANT DEPRESSION
- depression
- efficacy
- repetitive transcranial magnetic stimulation