TY - JOUR
T1 - Recovery of dialysis patients with COVID-19
T2 - Health outcomes 3 months after diagnosis in ERACODA
AU - Hemmelder, Marc H
AU - Noordzij, Marlies
AU - Vart, Priya
AU - Hilbrands, Luuk B
AU - Jager, Kitty J
AU - Abrahams, Alferso C
AU - Arroyo, David
AU - Battaglia, Yuri
AU - Ekart, Robert
AU - Mallamaci, Francesca
AU - Malloney, Sharon-Rose
AU - Oliveira, Joao
AU - Rydzewski, Andrzej
AU - Sridharan, Sivakumar
AU - Vogt, Liffert
AU - Duivenvoorden, Raphaël
AU - Gansevoort, Ron T
AU - Franssen, Casper F M
AU - ERACODA Collaborators
N1 - © The Author(s) 2022. Published by Oxford University Press on behalf of the ERA.
PY - 2022/6/1
Y1 - 2022/6/1
N2 - Background. Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. Methods. We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. Results. In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8–6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. Conclusions. Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis.
AB - Background. Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. Methods. We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. Results. In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8–6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. Conclusions. Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis.
KW - COVID-19
KW - KIDNEY-TRANSPLANT
KW - MORTALITY
KW - dialysis
KW - functional health status
KW - mental health status
KW - survival
KW - Covid-19
KW - Functional health status
KW - Dialysis
KW - Mental health status
KW - Survival
U2 - 10.1093/ndt/gfac008
DO - 10.1093/ndt/gfac008
M3 - Article
C2 - 35030246
SN - 0931-0509
VL - 37
SP - 1140
EP - 1151
JO - Nephrology Dialysis Transplantation
JF - Nephrology Dialysis Transplantation
IS - 6
ER -