Recovery of dialysis patients with COVID-19: Health outcomes 3 months after diagnosis in ERACODA

Marc H Hemmelder*, Marlies Noordzij, Priya Vart, Luuk B Hilbrands, Kitty J Jager, Alferso C Abrahams, David Arroyo, Yuri Battaglia, Robert Ekart, Francesca Mallamaci, Sharon-Rose Malloney, Joao Oliveira, Andrzej Rydzewski, Sivakumar Sridharan, Liffert Vogt, Raphaël Duivenvoorden, Ron T Gansevoort, Casper F M Franssen, ERACODA Collaborators

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background. Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. Methods. We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. Results. In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8–6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. Conclusions. Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis.

Original languageEnglish
Pages (from-to)1140-1151
Number of pages12
JournalNephrology Dialysis Transplantation
Volume37
Issue number6
Early online date14 Jan 2022
DOIs
Publication statusPublished - 1 Jun 2022

Keywords

  • COVID-19
  • KIDNEY-TRANSPLANT
  • MORTALITY
  • dialysis
  • functional health status
  • mental health status
  • survival
  • Covid-19
  • Functional health status
  • Dialysis
  • Mental health status
  • Survival

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