Abstract
From diagnostics to prognosis to response prediction, new applications for radiomics are rapidly being developed. One of the fastest evolving branches involves linking imaging phenotypes to the tumor genetic profile, a field commonly referred to as radiogenomics. In this review, a general outline of radiogenomic literature concerning prominent mutations across different tumor sites will be provided. The field of radiogenomics originates from image processing techniques developed decades ago; however, many technical and clinical challenges still need to be addressed. Nevertheless, increasingly accurate and robust radiogenomic models are being presented and the future appears to be bright.
Original language | English |
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Pages (from-to) | 1960-1984 |
Number of pages | 25 |
Journal | Abdominal Radiology |
Volume | 44 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1 Jun 2019 |
Keywords
- apparent diffusion-coefficient
- brain neoplasms
- breast neoplasms
- breast-cancer
- cell lung-cancer
- colorectal neoplasms
- factor receptor mutation
- gene-expression programs
- genomics
- hepatocellular-carcinoma
- kidney neoplasms
- liver neoplasms
- lower-grade gliomas
- lung neoplasms
- microvascular invasion
- pet radiomic features
- prostate neoplasms
- quantitative imaging
- quantitative texture analysis
- radiogenomics
- radiomics
- QUANTITATIVE TEXTURE ANALYSIS
- Genomics
- Colorectal neoplasms
- Radiomics
- BREAST-CANCER
- MICROVASCULAR INVASION
- HEPATOCELLULAR-CARCINOMA
- Prostate neoplasms
- Breast neoplasms
- Radiogenomics
- Liver neoplasms
- Kidney neoplasms
- PET RADIOMIC FEATURES
- APPARENT DIFFUSION-COEFFICIENT
- CELL LUNG-CANCER
- Brain neoplasms
- LOWER-GRADE GLIOMAS
- Quantitative imaging
- FACTOR RECEPTOR MUTATION
- GENE-EXPRESSION PROGRAMS
- Lung neoplasms