Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations

Michael J. Thrippleton*, Walter H. Backes, Steven Sourbron, Michael Ingrisch, Matthias J. P. van Osch, Martin Dichgans, Franz Fazekas, Stefan Ropele, Richard Frayne, Robert J. van Oostenbrugge, Eric E. Smith, Joanna M. Wardlaw

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Pages (from-to)840-858
Number of pages19
JournalAlzheimer's & Dementia
Volume15
Issue number6
DOIs
Publication statusPublished - Jun 2019

Keywords

  • Cerebral small vessel disease
  • Dementia
  • Blood-brain barrier
  • Endothelial dysfunction
  • DCE-MRI
  • Permeability
  • MRI
  • ENHANCED T-1-WEIGHTED MRI
  • ARTERIAL INPUT FUNCTION
  • WHITE-MATTER LESIONS
  • IN-VIVO
  • MULTIPLE-SCLEROSIS
  • ALZHEIMERS-DISEASE
  • WATER EXCHANGE
  • PERMEABILITY CHANGES
  • GA-68 EDTA

Cite this

Thrippleton, M. J., Backes, W. H., Sourbron, S., Ingrisch, M., van Osch, M. J. P., Dichgans, M., ... Wardlaw, J. M. (2019). Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations. Alzheimer's & Dementia, 15(6), 840-858. https://doi.org/10.1016/j.jalz.2019.01.013
Thrippleton, Michael J. ; Backes, Walter H. ; Sourbron, Steven ; Ingrisch, Michael ; van Osch, Matthias J. P. ; Dichgans, Martin ; Fazekas, Franz ; Ropele, Stefan ; Frayne, Richard ; van Oostenbrugge, Robert J. ; Smith, Eric E. ; Wardlaw, Joanna M. / Quantifying blood-brain barrier leakage in small vessel disease : Review and consensus recommendations. In: Alzheimer's & Dementia. 2019 ; Vol. 15, No. 6. pp. 840-858.
@article{600820bafae04a669786a963c05b7fcc,
title = "Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations",
keywords = "Cerebral small vessel disease, Dementia, Blood-brain barrier, Endothelial dysfunction, DCE-MRI, Permeability, MRI, ENHANCED T-1-WEIGHTED MRI, ARTERIAL INPUT FUNCTION, WHITE-MATTER LESIONS, IN-VIVO, MULTIPLE-SCLEROSIS, ALZHEIMERS-DISEASE, WATER EXCHANGE, PERMEABILITY CHANGES, GA-68 EDTA",
author = "Thrippleton, {Michael J.} and Backes, {Walter H.} and Steven Sourbron and Michael Ingrisch and {van Osch}, {Matthias J. P.} and Martin Dichgans and Franz Fazekas and Stefan Ropele and Richard Frayne and {van Oostenbrugge}, {Robert J.} and Smith, {Eric E.} and Wardlaw, {Joanna M.}",
year = "2019",
month = "6",
doi = "10.1016/j.jalz.2019.01.013",
language = "English",
volume = "15",
pages = "840--858",
journal = "Alzheimer's & Dementia",
issn = "1552-5260",
publisher = "Elsevier Science",
number = "6",

}

Thrippleton, MJ, Backes, WH, Sourbron, S, Ingrisch, M, van Osch, MJP, Dichgans, M, Fazekas, F, Ropele, S, Frayne, R, van Oostenbrugge, RJ, Smith, EE & Wardlaw, JM 2019, 'Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations', Alzheimer's & Dementia, vol. 15, no. 6, pp. 840-858. https://doi.org/10.1016/j.jalz.2019.01.013

Quantifying blood-brain barrier leakage in small vessel disease : Review and consensus recommendations. / Thrippleton, Michael J.; Backes, Walter H.; Sourbron, Steven; Ingrisch, Michael; van Osch, Matthias J. P.; Dichgans, Martin; Fazekas, Franz; Ropele, Stefan; Frayne, Richard; van Oostenbrugge, Robert J.; Smith, Eric E.; Wardlaw, Joanna M.

In: Alzheimer's & Dementia, Vol. 15, No. 6, 06.2019, p. 840-858.

Research output: Contribution to journalReview articleAcademicpeer-review

TY - JOUR

T1 - Quantifying blood-brain barrier leakage in small vessel disease

T2 - Review and consensus recommendations

AU - Thrippleton, Michael J.

AU - Backes, Walter H.

AU - Sourbron, Steven

AU - Ingrisch, Michael

AU - van Osch, Matthias J. P.

AU - Dichgans, Martin

AU - Fazekas, Franz

AU - Ropele, Stefan

AU - Frayne, Richard

AU - van Oostenbrugge, Robert J.

AU - Smith, Eric E.

AU - Wardlaw, Joanna M.

PY - 2019/6

Y1 - 2019/6

KW - Cerebral small vessel disease

KW - Dementia

KW - Blood-brain barrier

KW - Endothelial dysfunction

KW - DCE-MRI

KW - Permeability

KW - MRI

KW - ENHANCED T-1-WEIGHTED MRI

KW - ARTERIAL INPUT FUNCTION

KW - WHITE-MATTER LESIONS

KW - IN-VIVO

KW - MULTIPLE-SCLEROSIS

KW - ALZHEIMERS-DISEASE

KW - WATER EXCHANGE

KW - PERMEABILITY CHANGES

KW - GA-68 EDTA

U2 - 10.1016/j.jalz.2019.01.013

DO - 10.1016/j.jalz.2019.01.013

M3 - Review article

VL - 15

SP - 840

EP - 858

JO - Alzheimer's & Dementia

JF - Alzheimer's & Dementia

SN - 1552-5260

IS - 6

ER -