Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations

Michael J. Thrippleton*, Walter H. Backes, Steven Sourbron, Michael Ingrisch, Matthias J. P. van Osch, Martin Dichgans, Franz Fazekas, Stefan Ropele, Richard Frayne, Robert J. van Oostenbrugge, Eric E. Smith, Joanna M. Wardlaw

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Pages (from-to)840-858
Number of pages19
JournalAlzheimer's & Dementia
Volume15
Issue number6
DOIs
Publication statusPublished - Jun 2019

Keywords

  • Cerebral small vessel disease
  • Dementia
  • Blood-brain barrier
  • Endothelial dysfunction
  • DCE-MRI
  • Permeability
  • MRI
  • ENHANCED T-1-WEIGHTED MRI
  • ARTERIAL INPUT FUNCTION
  • WHITE-MATTER LESIONS
  • IN-VIVO
  • MULTIPLE-SCLEROSIS
  • ALZHEIMERS-DISEASE
  • WATER EXCHANGE
  • PERMEABILITY CHANGES
  • GA-68 EDTA

Cite this

Thrippleton, M. J., Backes, W. H., Sourbron, S., Ingrisch, M., van Osch, M. J. P., Dichgans, M., Fazekas, F., Ropele, S., Frayne, R., van Oostenbrugge, R. J., Smith, E. E., & Wardlaw, J. M. (2019). Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations. Alzheimer's & Dementia, 15(6), 840-858. https://doi.org/10.1016/j.jalz.2019.01.013