TY - JOUR
T1 - Quality of life and psychosocial outcomes in children with severe acute asthma and their parents
AU - Boeschoten, Shelley A.
AU - Dulfer, Karolijn
AU - Boehmer, Annemie L.M.
AU - Merkus, Peter J.F.M.
AU - van Rosmalen, Joost
AU - de Jongste, Johan C.
AU - de Hoog, Matthijs
AU - Buysse, Corinne M.P.
AU - Heisterkamp, Sabien
AU - van Woensel, Job
AU - Haarman, Eric
AU - Kapitein, Berber
AU - Wösten-van Asperen, Roelie
AU - Kneyber, Martin
AU - Lemson, Joris
AU - Hartman, Stan
AU - van Waardenburg, Dick
AU - Bunker, Heleen
AU - Brouwer, Carole
AU - van Ewijk, Bart
AU - Landstra, Anneke
AU - Verwaal, Mariel
AU - Vaessen-Verberne, Anja
AU - Hammer, Sanne
AU - Dutch collaborative PICU research network (SKIC)
N1 - Funding Information:
This study was financially supported by the Dutch Foundation for Asthma Prevention (Stichting Astma Bestrijding), Ammodo (Institute of Art and Science), unrestricted grants of Chiesi Pharmaceuticals BV Netherlands and Novartis Pharma, B.V. The Netherlands.
Funding Information:
This study was financially supported by the Dutch Foundation for Asthma Prevention (Stichting Astma Bestrijding), Ammodo (Institute of Art and Science), unrestricted grants of Chiesi Pharmaceuticals BV Netherlands and Novartis Pharma, B.V. The Netherlands. Research consortium SKIC members (Dutch Collaborative PICU Research Network): Amsterdam University Medical Centers, Amsterdam, The Netherlands: Sabien Heisterkamp, Job van Woensel, Eric Haarman and Berber Kapitein; Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, The Netherlands: Roelie Wösten-van Asperen; Beatrix Children's Hospital/University Medical Center Groningen, Groningen, The Netherlands: Martin Kneyber; University Medical Center Nijmegen, Nijmegen, The Netherlands: Joris Lemson and Stan Hartman; Maastricht University Medical Center, Maastricht, The Netherlands: Dick van Waardenburg; Leiden University Medical Center, Leiden, The Netherlands: Heleen Bunker and Carole Brouwer; Tergooi Hospital, Blaricum, The Netherlands: Bart van Ewijk; Rijnstate Hospital, Arnhem, The Netherlands: Anneke Landstra; Maasstad Hospital, Rotterdam, The Netherlands: Mariel Verwaal; and Amphia Hospital, Breda, The Netherlands: Anja Vaessen-Verberne and Sanne Hammer.
Publisher Copyright:
© 2020 The Authors. Pediatric Pulmonology published by Wiley Periodicals LLC
PY - 2020/11/1
Y1 - 2020/11/1
N2 - Objectives: To prospectively evaluate quality of life (QoL) and psychosocial outcomes in children with severe acute asthma (SAA) after pediatric intensive care (PICU) admission compared to children with SAA who were admitted to a general ward (GW). In addition, we assessed posttraumatic stress (PTS) and asthma-related QoL in the parents. Methods: A preplanned follow-up of 3 to 9 months of our nationwide prospective multicenter study, in which children with SAA admitted to a Dutch PICU (n = 110) or GW (n = 111) were enrolled between 2016 and 2018. Asthma-related QoL, PTS symptoms, emotional and behavioral problems, and social impact in children and/or parents were assessed with validated web-based questionnaires. Results: We included 100 children after PICU and 103 after GW admission, with a response rate of 50% for the questionnaires. Median time to follow-up was 5 months (range: 1-12 months). Time to reach full schooldays after admission was significantly longer in the PICU group (mean of 10 vs 4 days, P =.001). Parents in the PICU group reported more PTS symptoms (intrusion P =.01, avoidance P =.01, arousal P =.02) compared to the GW group. Conclusion: No significant differences were found between PICU and GW children on self-reported outcome domains, except for the time to reach full schooldays. PICU parents reported PTS symptoms more often than the GW group. Therefore, monitoring asthma symptoms and psychosocial screening of children and parents after PICU admission should both be part of standard care after SAA. This should identify those who are at risk for developing PTSD, to timely provide appropriate interventions.
AB - Objectives: To prospectively evaluate quality of life (QoL) and psychosocial outcomes in children with severe acute asthma (SAA) after pediatric intensive care (PICU) admission compared to children with SAA who were admitted to a general ward (GW). In addition, we assessed posttraumatic stress (PTS) and asthma-related QoL in the parents. Methods: A preplanned follow-up of 3 to 9 months of our nationwide prospective multicenter study, in which children with SAA admitted to a Dutch PICU (n = 110) or GW (n = 111) were enrolled between 2016 and 2018. Asthma-related QoL, PTS symptoms, emotional and behavioral problems, and social impact in children and/or parents were assessed with validated web-based questionnaires. Results: We included 100 children after PICU and 103 after GW admission, with a response rate of 50% for the questionnaires. Median time to follow-up was 5 months (range: 1-12 months). Time to reach full schooldays after admission was significantly longer in the PICU group (mean of 10 vs 4 days, P =.001). Parents in the PICU group reported more PTS symptoms (intrusion P =.01, avoidance P =.01, arousal P =.02) compared to the GW group. Conclusion: No significant differences were found between PICU and GW children on self-reported outcome domains, except for the time to reach full schooldays. PICU parents reported PTS symptoms more often than the GW group. Therefore, monitoring asthma symptoms and psychosocial screening of children and parents after PICU admission should both be part of standard care after SAA. This should identify those who are at risk for developing PTSD, to timely provide appropriate interventions.
KW - follow-up
KW - parents
KW - PICU
KW - status asthmaticus
U2 - 10.1002/ppul.25034
DO - 10.1002/ppul.25034
M3 - Article
SN - 8755-6863
VL - 55
SP - 2883
EP - 2892
JO - Pediatric Pulmonology
JF - Pediatric Pulmonology
IS - 11
ER -