Preliminary study on the assessment of visceral adipose tissue using dual-energy x-ray absorptiometry in chronic obstructive pulmonary disease

Francesca De Blasio*, Erica Rutten, Emiel F. M. Wouters, Luca Scalfi, Francesco De Blasio, Marco A. Akkermans, Martijn A. Spruit, Frits M. E. Franssen

*Corresponding author for this work

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Abstract

Visceral adipose tissue (VAT) was shown to be increased in patients with chronic obstructive pulmonary disease (COPD) compared to control subjects with comparable body mass index (BMI). Our aim was to determine the relation of VAT by dual-energy x-ray absorptiometry (DEXA) in patients with COPD by disease severity, BMI, other indices of body composition and static lung volumes.294 COPD patients admitted for rehabilitation were studied. Lung function, static lung volumes and body composition (i.e. BMI, waist circumference, fat-free mass, fat mass and fat distribution between android and gynoid fat mass) were assessed before entering pulmonary rehabilitation. VAT was estimated within the android region by using DEXA. Patients were stratified for gender, BMI (cut-off of 25?kg/m2) and GOLD stage. To assess the impact of VAT on lung volumes, patients were also stratified for VAT less and above 50th percentile.Both male and female patients with more severe airflow limitation had significantly lower VAT values, but these differences disappeared after stratification for BMI. VAT was significantly and strongly correlated with other body composition parameters (all p?
Original languageEnglish
Article number33
JournalMultidisciplinary Respiratory Medicine
Volume11
DOIs
Publication statusPublished - 4 Oct 2016

Keywords

  • Body composition
  • COPD
  • DEXA
  • Fat mass
  • Visceral adipose tissue

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