Postoperative circadian patterns in wearable sensor measured heart rate: a prospective observational study

Eveline H.J. Mestrom*, Jonna A. van der Stam, Simon W. Nienhuijs, Ignace H.J.T. de Hingh, Arjen Kars Boer, Natal A.W. van Riel, Volkher Scharnhorst, R. Arthur Bouwman

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Purpose: This study aimed to describe the 24-hour cycle of wearable sensor-obtained heart rate in patients with deterioration-free recovery and to compare it with patients experiencing postoperative deterioration. Methods: A prospective observational trial was performed in patients following bariatric or major abdominal cancer surgery. A wireless accelerometer patch (Healthdot) continuously measured postoperative heart rate, both in the hospital and after discharge, for a period of 14 days. The circadian pattern, or diurnal rhythm, in the wearable sensor-obtained heart rate was described using peak, nadir and peak-nadir excursions. Results: The study population consisted of 137 bariatric and 100 major abdominal cancer surgery patients. In the latter group, 39 experienced postoperative deterioration. Both surgery types showed disrupted diurnal rhythm on the first postoperative days. Thereafter, the bariatric group had significantly lower peak heart rates (days 4, 7–12, 14), lower nadir heart rates (days 3–14) and larger peak-nadir excursions (days 2, 4–14). In cancer surgery patients, significantly higher nadir (days 2–5) and peak heart rates (days 2–3) were observed prior to deterioration. Conclusions: The postoperative diurnal rhythm of heart rate is disturbed by different types of surgery. Both groups showed recovery of diurnal rhythm but in patients following cancer surgery, both peak and nadir heart rates were higher than in the bariatric surgery group. Especially nadir heart rate was identified as a potential prognostic marker for deterioration after cancer surgery.
Original languageEnglish
Pages (from-to)147-156
Number of pages10
JournalJournal of Clinical Monitoring and Computing
Volume38
Issue number1
Early online date21 Oct 2023
DOIs
Publication statusPublished - Feb 2024

Keywords

  • Circadian patterns
  • Continuous monitoring
  • Deterioration
  • Diurnal rhythm
  • Early warning score
  • Postoperative patients
  • Wearable sensor

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