TY - JOUR
T1 - Point-of-care testing di troponina ad alta sensibilità (hs-ctn Poct)
T2 - stato dell’arte e prospettive
AU - Morandini, Margherita
AU - Cappelletti, Piero
AU - Moretti, Marco
AU - Manno, Massimiliano
AU - Stenner, Elisabetta
AU - Malloggi, Lucia
AU - Veneziani, Francesca
AU - Burgio, Maria A.
AU - Di Pietro, Martina
AU - Biondi, Maria L.
AU - Rubin, Daniela
AU - Viola, Jessica
AU - Marino, Giulio
AU - Di Maria, Dina
AU - Mazzei, Deborah
AU - Gamboni, Alessio
AU - Fina, Dario
AU - Cassin, Matteo
AU - Galli, Gianni A.
AU - Gruppo di Studio sui Marcatori Miocardici (GdS MM) della Società Italiana di Patologia Clinica e Medicina di Laboratorio (SIPMeL)
N1 - Publisher Copyright:
© 2023 EDIZIONI MINERVA MEDICA.
PY - 2022/12/1
Y1 - 2022/12/1
N2 - The rationale for the Point-of-care testing (POCT) of troponin (cTn) lies in the reduction of the Turnaround Time (TAT) and therefore of the length-of-stay (LOS) in the Emergency Department (ED), and in the diagnosis of heart injury in isolated areas. However, cTn POCTs are less sensitive and not comparable with laboratory methods (LAB). Their data cannot be used in the troponin curve with the LAB method and the rise and fall curve with POCT must be followed for more than 6 hours. Furthermore, there are few primary evidence and no meta-analyses on the role of cTn POCTs. Nevertheless, POCTs with hs-cTn (high-sensitivity troponin) method have recently appeared on the market and can overcome the above-described issues: PATHFAST hs-cTn, Quiedel/Alere TriageTrue, Atellica VTLi Patient-side. The Review describes the data and evidence of these devices, evaluating their adequacy for the diagnostic objectives, and their perspectives.
AB - The rationale for the Point-of-care testing (POCT) of troponin (cTn) lies in the reduction of the Turnaround Time (TAT) and therefore of the length-of-stay (LOS) in the Emergency Department (ED), and in the diagnosis of heart injury in isolated areas. However, cTn POCTs are less sensitive and not comparable with laboratory methods (LAB). Their data cannot be used in the troponin curve with the LAB method and the rise and fall curve with POCT must be followed for more than 6 hours. Furthermore, there are few primary evidence and no meta-analyses on the role of cTn POCTs. Nevertheless, POCTs with hs-cTn (high-sensitivity troponin) method have recently appeared on the market and can overcome the above-described issues: PATHFAST hs-cTn, Quiedel/Alere TriageTrue, Atellica VTLi Patient-side. The Review describes the data and evidence of these devices, evaluating their adequacy for the diagnostic objectives, and their perspectives.
KW - Acute coronary syndrome
KW - Point-of-care testing
KW - Troponin
U2 - 10.23736/S1825-859X.23.00173-1
DO - 10.23736/S1825-859X.23.00173-1
M3 - (Systematic) Review article
SN - 1825-859X
VL - 18
SP - 186
EP - 195
JO - Rivista Italiana della Medicina di Laboratorio
JF - Rivista Italiana della Medicina di Laboratorio
IS - 4
ER -