Peripheral DNA methylation, cognitive decline and brain aging: pilot findings from the Whitehall II imaging study

Leonidas Chouliaras*, Ehsan Pishva, Rita Haapakoski, Eniko Zsoldos, Abda Mahmood, Nicola Filippini, Joe Burrage, Jonathan Mill, Mika Kivimaki, Katie Lunnon, Klaus P. Ebmeier

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)585-595
Number of pages11
JournalEpigenomics
Volume10
Issue number5
DOIs
Publication statusPublished - 1 May 2018

Keywords

  • brain aging
  • DNA methylation
  • epigenetic clock
  • MCI
  • mild cognitive impairment
  • MRI
  • peripheral biomarker
  • MESSENGER-RNA EXPRESSION
  • ALZHEIMERS-DISEASE
  • INTRON 1
  • BLOOD
  • DEMENTIA
  • TREM2
  • AGE
  • DYSREGULATION
  • HIPPOCAMPUS
  • ENRICHMENT

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