Peripheral DNA methylation, cognitive decline and brain aging: pilot findings from the Whitehall II imaging study

Leonidas Chouliaras, Ehsan Pishva, Rita Haapakoski, Eniko Zsoldos, Abda Mahmood, Nicola Filippini, Joe Burrage, Jonathan Mill, Mika Kivimaki, Katie Lunnon, Klaus P. Ebmeier

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)585-595
Number of pages11
JournalEpigenomics
Volume10
Issue number5
DOIs
Publication statusPublished - 1 May 2018

Keywords

  • brain aging
  • DNA methylation
  • epigenetic clock
  • MCI
  • mild cognitive impairment
  • MRI
  • peripheral biomarker
  • MESSENGER-RNA EXPRESSION
  • ALZHEIMERS-DISEASE
  • INTRON 1
  • BLOOD
  • DEMENTIA
  • TREM2
  • AGE
  • DYSREGULATION
  • HIPPOCAMPUS
  • ENRICHMENT

Cite this

Chouliaras, L., Pishva, E., Haapakoski, R., Zsoldos, E., Mahmood, A., Filippini, N., Burrage, J., Mill, J., Kivimaki, M., Lunnon, K., & Ebmeier, K. P. (2018). Peripheral DNA methylation, cognitive decline and brain aging: pilot findings from the Whitehall II imaging study. Epigenomics, 10(5), 585-595. https://doi.org/10.2217/epi-2017-0132