Paternal impact on genetic integrity in newborns.

J.O. Linschooten

doi:10.26481/dis.20120620jol

Paternal impact on genetic integrity in newborns.

J.O. Linschooten

Research output: Thesis › Doctoral Thesis › Internal

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Abstract

The quality of the DNA in sperm from potential fathers is under constant pressure because it is exposed to a great diversity of harmful substances. This can lead to transmission of DNA damage to the offspring with long-lasting health consequences. The research for this dissertation shows that a lifestyle with bad habits, such as smoking, has indeed a harmful effect on the DNA in the sperm. Even more important is that subsequently an indication was found for genetic effects of this damage in the offspring.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	Maastricht University
Supervisors/Advisors	van Schooten, Frederik, Supervisor Godschalk, Roger, Co-Supervisor
Award date	20 Jun 2012
Place of Publication	Maastricht
Publisher	Datawyse / Universitaire Pers Maastricht
Print ISBNs	9789088914362
DOIs	https://doi.org/10.26481/dis.20120620jol
Publication status	Published - 1 Jan 2012

Keywords

DNA
sperm
health

Access to Document

10.26481/dis.20120620jol

Full TextFinal published version, 12.1 MB
CoverFinal published version, 62.7 KB
AbstractFinal published version, 219 KB
PropositionsFinal published version, 62.7 KB

Cite this

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