Novel insights into the health effects of fruits and vegetables: challenging the status quo

Hidde Pieter van Steenwijk

Research output: Thesis › Doctoral Thesis › Internal

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Abstract

The research described in this thesis showed that inflammation-related effects of phytonutrients from vegetables can be studied within hours in healthy participants. The use of integrative outcomes measures, as well as non-invasive biomarkers, such as 11-dehydro-TXB2 and HRV monitoring, may offer improved ways of measuring and reporting the subtle and pleiotropic effects of nutrition on inflammation. Considering, validating, and adopting innovative integrative research approaches (e.g. composite scores, wearables, n-of-1 designs) would enhance our understanding of the hormetic principles of bioactive compounds and provide the much-needed evidence to develop research portfolios that will inform new product development and associated health claims.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • Bast, Aalt, Supervisor
  • de Boer, Alie, Co-Supervisor
  • Semen, Khrystyna, Co-Supervisor
Award date30 Nov 2023
Place of PublicationMaastricht
Publisher
Print ISBNs9789464695854
DOIs
Publication statusPublished - 2023

Keywords

  • Inflammation
  • Non-communicable diseases
  • Lifestyle prevention
  • Phytonutrients

Access to Document

  • Full TextFinal published version, 10.8 MB
  • SummaryFinal published version, 147 KB
  • PropositionsFinal published version, 125 KB
  • CoverFinal published version, 483 KB
  • ImpactFinal published version, 1.58 MB

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