Nonclinical regulatory immunotoxicity testing of nanomedicinal products: Proposed strategy and possible pitfalls

Christina Giannakou, Margriet V. D. Z. Park*, Irene E. M. Bosselaers, Wim H. de Jong, Jan Willem van der Laan, Henk van Loveren, Rob J. Vandebriel, Robert E. Geertsma

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Original languageEnglish
Article number1633
Number of pages16
JournalWiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
Volume12
Issue number5
DOIs
Publication statusPublished - Sep 2020

Keywords

  • ICH-S8
  • immunotoxicity
  • in vitro
  • nanomedicinal product
  • regulatory
  • COMPLEMENT ACTIVATION
  • SILVER NANOPARTICLES
  • TISSUE DISTRIBUTION
  • SKIN INTERACTIONS
  • IN-VITRO
  • TOXICITY
  • INFLAMMASOME
  • ACCUMULATION
  • DISEASE

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