Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis

Nadine Rohwer, Sandra Jumpertz, Merve Erdem, Antje Egners, Klaudia T. Warzecha, Athanassios Fragoulis, Anja A. Kuehl, Rafael Kramann, Sabine Neuss, Ines Rudolph, Tobias Endermann, Christin Zasada, Ivayla Apostolova, Marco Gerling, Stefan Kempa, Russell Hughes, Claire E. Lewis, Winfried Brenner, Maciej B. Malinowski, Martin StockmannLutz Schomburg, William Faller, Owen J. Sansom, Frank Tacke, Markus Morkel, Thorsten Cramer*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)5670-5685
Number of pages16
JournalOncogene
Volume38
Issue number28
DOIs
Publication statusPublished - 11 Jul 2019

Keywords

  • HYPOXIA-INDUCIBLE FACTOR-1-ALPHA
  • CARCINOMA-ASSOCIATED FIBROBLASTS
  • TUMOR-ASSOCIATED MACROPHAGES
  • TARGETED CANCER-THERAPY
  • DENDRITIC CELLS
  • POOR-PROGNOSIS
  • MURINE MODEL
  • MOUSE MODEL
  • STEM-CELLS
  • FACTOR-I

Cite this

Rohwer, N., Jumpertz, S., Erdem, M., Egners, A., Warzecha, K. T., Fragoulis, A., Kuehl, A. A., Kramann, R., Neuss, S., Rudolph, I., Endermann, T., Zasada, C., Apostolova, I., Gerling, M., Kempa, S., Hughes, R., Lewis, C. E., Brenner, W., Malinowski, M. B., ... Cramer, T. (2019). Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis. Oncogene, 38(28), 5670-5685. https://doi.org/10.1038/s41388-019-0816-4