Nintedanib reduces radiation -induced microscopic lung fibrosis but this cannot be monitored by CT imaging: A preclinical study with a high precision image-guided irradiator

Dirk De Ruysscher, Patrick Vincent Granton, Natasja Gaby Lieuwes, Stefan van Hoof, Lutz Wollin, Birgit Weynand, Anne-Marie Dingemans, Frank Verhaegen, Ludwig Dubois*

*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original languageEnglish
Pages (from-to)482-487
Number of pages6
JournalRadiotherapy and Oncology
Volume124
Issue number3
DOIs
Publication statusPublished - Sep 2017
Event15th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology - SWITZERLAND, Switzerland
Duration: 17 Jun 2017 → 19 Jun 2017

Keywords

  • Nintedanib
  • Radiation-induced lung damage
  • Radiation pneumonitis
  • Radiation fibrosis
  • Small animal image-guided precision irradiation
  • IDIOPATHIC PULMONARY-FIBROSIS
  • THORACIC IRRADIATION
  • RADIOTHERAPY
  • THERAPIES
  • DAMAGE
  • MICE
  • PNEUMONITIS
  • PROGRESSION
  • STRAINS
  • SEARCH

Cite this

De Ruysscher, Dirk ; Granton, Patrick Vincent ; Lieuwes, Natasja Gaby ; van Hoof, Stefan ; Wollin, Lutz ; Weynand, Birgit ; Dingemans, Anne-Marie ; Verhaegen, Frank ; Dubois, Ludwig. / Nintedanib reduces radiation -induced microscopic lung fibrosis but this cannot be monitored by CT imaging : A preclinical study with a high precision image-guided irradiator. In: Radiotherapy and Oncology. 2017 ; Vol. 124, No. 3. pp. 482-487.
@article{42bd00e65a4b49a0b556cfb0e7b8882e,
title = "Nintedanib reduces radiation -induced microscopic lung fibrosis but this cannot be monitored by CT imaging: A preclinical study with a high precision image-guided irradiator",
keywords = "Nintedanib, Radiation-induced lung damage, Radiation pneumonitis, Radiation fibrosis, Small animal image-guided precision irradiation, IDIOPATHIC PULMONARY-FIBROSIS, THORACIC IRRADIATION, RADIOTHERAPY, THERAPIES, DAMAGE, MICE, PNEUMONITIS, PROGRESSION, STRAINS, SEARCH",
author = "{De Ruysscher}, Dirk and Granton, {Patrick Vincent} and Lieuwes, {Natasja Gaby} and {van Hoof}, Stefan and Lutz Wollin and Birgit Weynand and Anne-Marie Dingemans and Frank Verhaegen and Ludwig Dubois",
year = "2017",
month = "9",
doi = "10.1016/j.radonc.2017.07.014",
language = "English",
volume = "124",
pages = "482--487",
journal = "Radiotherapy and Oncology",
issn = "0167-8140",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

De Ruysscher, D, Granton, PV, Lieuwes, NG, van Hoof, S, Wollin, L, Weynand, B, Dingemans, A-M, Verhaegen, F & Dubois, L 2017, 'Nintedanib reduces radiation -induced microscopic lung fibrosis but this cannot be monitored by CT imaging: A preclinical study with a high precision image-guided irradiator', Radiotherapy and Oncology, vol. 124, no. 3, pp. 482-487. https://doi.org/10.1016/j.radonc.2017.07.014

Nintedanib reduces radiation -induced microscopic lung fibrosis but this cannot be monitored by CT imaging : A preclinical study with a high precision image-guided irradiator. / De Ruysscher, Dirk; Granton, Patrick Vincent; Lieuwes, Natasja Gaby; van Hoof, Stefan; Wollin, Lutz; Weynand, Birgit; Dingemans, Anne-Marie; Verhaegen, Frank; Dubois, Ludwig.

In: Radiotherapy and Oncology, Vol. 124, No. 3, 09.2017, p. 482-487.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Nintedanib reduces radiation -induced microscopic lung fibrosis but this cannot be monitored by CT imaging

T2 - A preclinical study with a high precision image-guided irradiator

AU - De Ruysscher, Dirk

AU - Granton, Patrick Vincent

AU - Lieuwes, Natasja Gaby

AU - van Hoof, Stefan

AU - Wollin, Lutz

AU - Weynand, Birgit

AU - Dingemans, Anne-Marie

AU - Verhaegen, Frank

AU - Dubois, Ludwig

PY - 2017/9

Y1 - 2017/9

KW - Nintedanib

KW - Radiation-induced lung damage

KW - Radiation pneumonitis

KW - Radiation fibrosis

KW - Small animal image-guided precision irradiation

KW - IDIOPATHIC PULMONARY-FIBROSIS

KW - THORACIC IRRADIATION

KW - RADIOTHERAPY

KW - THERAPIES

KW - DAMAGE

KW - MICE

KW - PNEUMONITIS

KW - PROGRESSION

KW - STRAINS

KW - SEARCH

U2 - 10.1016/j.radonc.2017.07.014

DO - 10.1016/j.radonc.2017.07.014

M3 - Article

VL - 124

SP - 482

EP - 487

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

SN - 0167-8140

IS - 3

ER -

De Ruysscher D, Granton PV, Lieuwes NG, van Hoof S, Wollin L, Weynand B et al. Nintedanib reduces radiation -induced microscopic lung fibrosis but this cannot be monitored by CT imaging: A preclinical study with a high precision image-guided irradiator. Radiotherapy and Oncology. 2017 Sep;124(3):482-487. https://doi.org/10.1016/j.radonc.2017.07.014

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