New developments in nasopharyngeal cancer

Ing Bing Tan, Norhafiza Mat Lazim, Sharon D. Stoker, Maarten A. Wildeman

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

This chapter discusses the new developments in diagnosis and treatment of nasopharyngeal carcinoma (NPC). NPC is strongly related to the Epstein-Barr virus (EBV), especially in the high endemic regions of Asia. Therefore EBV is a major topic of interest in improving early diagnosis, follow-up, and development of new treatment opportunities. The emergence of new imaging modalities, organ preservation protocols, and well-equipped centers of expertise around the globe have in part enhanced the treatment of NPC patients. Extensive research continues to evolve to treat patients with relapsing local, regional, or metastasized disease. In addition to advanced surgery and radiation techniques, photodynamic therapy and immunotherapy are being explored to give patients with NPC a better prognosis and survival. This chapter will discuss the aforementioned issues in depth and focus on specific updates in the diagnosis, follow-up as well as treatment strategies of NPC.
Original languageEnglish
Title of host publicationAn Evidence-Based Approach to the Management of Nasopharyngeal Cancer: From Basic Science to Clinical Presentation and Treatment
EditorsBaharudin Abdullah, Anusha Balasubramanian, Norhafiza Mat Lazim
PublisherElsevier
Chapter14
Pages277-299
Number of pages23
ISBN (Electronic)9780128144039
ISBN (Print)9780128144046
DOIs
Publication statusPublished - 1 Jan 2020

Keywords

  • chemoradiation
  • Epstein-Barr virus
  • immunotherapy
  • Nasopharyngeal carcinoma
  • organ preservation protocol
  • targeted therapy

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