TY - JOUR
T1 - Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects
AU - Brouwer, Brigitte A.
AU - de Greef, Bianca T. A.
AU - Hoeijmakers, Janneke G. J.
AU - Geerts, Margot
AU - van Kleef, Maarten
AU - Merkies, Ingemar S. J.
AU - Faber, Catharina G.
PY - 2015/8
Y1 - 2015/8
N2 - Over the last 10 years, the diagnosis small fiber neuropathy (SFN) has gained recognition worldwide. Patients often suffer from severe neuropathic pain that may be difficult to treat. A substantial subset of patients with SFN is aged 65 years or older, and these patients often exhibit comorbidities and usage of multiple drugs, making neuropathic pain treatment more challenging. In this review, we highlight relevant pathophysiological aspects and discuss currently used therapeutic strategies for neuropathic pain. Possible pitfalls in neuropathic pain treatment in the elderly will be underlined.
AB - Over the last 10 years, the diagnosis small fiber neuropathy (SFN) has gained recognition worldwide. Patients often suffer from severe neuropathic pain that may be difficult to treat. A substantial subset of patients with SFN is aged 65 years or older, and these patients often exhibit comorbidities and usage of multiple drugs, making neuropathic pain treatment more challenging. In this review, we highlight relevant pathophysiological aspects and discuss currently used therapeutic strategies for neuropathic pain. Possible pitfalls in neuropathic pain treatment in the elderly will be underlined.
U2 - 10.1007/s40266-015-0283-8
DO - 10.1007/s40266-015-0283-8
M3 - Article
C2 - 26239827
SN - 1170-229X
VL - 32
SP - 611
EP - 621
JO - Drugs & Aging
JF - Drugs & Aging
IS - 8
ER -