TY - JOUR
T1 - National, sub-national, and risk-attributed burden of thyroid cancer in Iran from 1990 to 2019
AU - Azangou-Khyavy, Mohammadreza
AU - Saeedi Moghaddam, Sahar
AU - Rezaei, Negar
AU - Esfahani, Zahra
AU - Azadnajafabad, Sina
AU - Rashidi, Mohammad Mahdi
AU - Mohammadi, Esmaeil
AU - Rezaei, Nazila
AU - Abbasi-Kangevari, Mohsen
AU - Abbasi-Kangevari, Zeinab
AU - Abolhassani, Hassan
AU - Ahmadi, Sepideh
AU - Ahmadi, Ali
AU - Amini, Saeed
AU - Amlashi, Fazel Isapanah
AU - Anoushirvani, Ali Arash
AU - Arabloo, Jalal
AU - Athari, Seyyed Shamsadin
AU - Jafari, Amirhossein Azari
AU - Besharat, Sima
AU - Bijani, Ali
AU - Daryani, Ahmad
AU - Dianatinasab, Mostafa
AU - Didehdar, Mojtaba
AU - Fatehizadeh, Ali
AU - Ghamari, Seyyed Hadi
AU - Ghashghaee, Ahmad
AU - Goleij, Pouya
AU - Golitaleb, Mohamad
AU - Hafezi-Nejad, Nima
AU - Haj-Mirzaian, Arvin
AU - Hassanipour, Soheil
AU - Kabir, Ali
AU - Keramati, Maryam
AU - Khalilov, Rovshan
AU - Khayamzadeh, Maryam
AU - Kolahi, Ali Asghar
AU - Kompani, Farzad
AU - Koohestani, Hamid Reza
AU - Livani, Somayeh
AU - Mahjoub, Soleiman
AU - Malekpour, Mohammad Reza
AU - GBD 2019 Iran Thyroid Cancer Collaborators
N1 - Funding Information:
The authors thank the Institute for Health Metrics and Evaluation (IHME) for data provision. Also, authors sincerely thank all the collaborators contributed to this study at Non-Communicable Diseases Research Center (NCDRC) of Endocrinology and Metabolism Research Institute (EMRI) at Tehran University of Medical Sciences.
Publisher Copyright:
© 2022, The Author(s).
PY - 2022/8/2
Y1 - 2022/8/2
N2 - An updated exploration of the burden of thyroid cancer across a country is always required for making correct decisions. The objective of this study is to present the thyroid cancer burden and attributed burden to the high Body Mass Index (BMI) in Iran at national and sub-national levels from 1990 to 2019. The data was obtained from the GBD 2019 study estimates. To explain the pattern of changes in incidence from 1990 to 2019, decomposition analysis was conducted. Besides, the attribution of high BMI in the thyroid cancer DALYs and deaths were obtained. The age-standardized incidence rate of thyroid cancer was 1.57 (95% UI: 1.33–1.86) in 1990 and increased 131% (53–191) until 2019. The age-standardized prevalence rate of thyroid cancer was 30.19 (18.75–34.55) in 2019 which increased 164% (77–246) from 11.44 (9.38–13.85) in 1990. In 2019, the death rate, and Disability-adjusted life years of thyroid cancer was 0.49 (0.36–0.53), and 13.16 (8.93–14.62), respectively. These numbers also increased since 1990. The DALYs and deaths attributable to high BMI was 1.91 (0.95–3.11) and 0.07 (0.04–0.11), respectively. The thyroid cancer burden and high BMI attributed burden has increased from 1990 to 2019 in Iran. This study and similar studies’ results can be used for accurate resource allocation for efficient management and all potential risks’ modification for thyroid cancer with a cost-conscious view.
AB - An updated exploration of the burden of thyroid cancer across a country is always required for making correct decisions. The objective of this study is to present the thyroid cancer burden and attributed burden to the high Body Mass Index (BMI) in Iran at national and sub-national levels from 1990 to 2019. The data was obtained from the GBD 2019 study estimates. To explain the pattern of changes in incidence from 1990 to 2019, decomposition analysis was conducted. Besides, the attribution of high BMI in the thyroid cancer DALYs and deaths were obtained. The age-standardized incidence rate of thyroid cancer was 1.57 (95% UI: 1.33–1.86) in 1990 and increased 131% (53–191) until 2019. The age-standardized prevalence rate of thyroid cancer was 30.19 (18.75–34.55) in 2019 which increased 164% (77–246) from 11.44 (9.38–13.85) in 1990. In 2019, the death rate, and Disability-adjusted life years of thyroid cancer was 0.49 (0.36–0.53), and 13.16 (8.93–14.62), respectively. These numbers also increased since 1990. The DALYs and deaths attributable to high BMI was 1.91 (0.95–3.11) and 0.07 (0.04–0.11), respectively. The thyroid cancer burden and high BMI attributed burden has increased from 1990 to 2019 in Iran. This study and similar studies’ results can be used for accurate resource allocation for efficient management and all potential risks’ modification for thyroid cancer with a cost-conscious view.
U2 - 10.1038/s41598-022-17115-0
DO - 10.1038/s41598-022-17115-0
M3 - Article
C2 - 35918489
SN - 2045-2322
VL - 12
JO - Scientific Reports
JF - Scientific Reports
IS - 1
M1 - 13231
ER -