Mycoplasma pneumoniae and Chlamydia spp. Infection in Community-Acquired Pneumonia, Germany, 2011-2012

R. Dumke, C. Schnee, M.W. Pletz, J. Rupp, E. Jacobs, K. Sachse, G. Rohde, C.S. Group

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Abstract

Mycoplasma pneumoniae and Chlamydia spp., which are associated with community-acquired pneumonia (CAP), are difficult to propagate, and can cause clinically indistinguishable disease patterns. During 2011-2012, we used molecular methods to test adult patients in Germany with confirmed CAP for infection with these 2 pathogens. Overall, 12.3% (96/783) of samples were positive for M. pneumoniae and 3.9% (31/794) were positive for Chlamydia spp.; C. psittaci (2.1%) was detected more frequently than C. pneumoniae (1.4%). M. pneumoniae P1 type 1 predominated, and levels of macrolide resistance were low (3.1%). Quarterly rates of M. pneumoniae-positive samples ranged from 1.5% to 27.3%, showing a strong epidemic peak for these infections, but of Chlamydia spp. detection was consistent throughout the year. M. pneumoniae-positive patients were younger and more frequently female, had fewer co-occurring conditions, and experienced milder disease than did patients who tested negative. Clinicians should be aware of the epidemiology of these pathogens in CAP.
Original languageEnglish
Pages (from-to)426-434
Number of pages9
JournalEmerging Infectious Diseases
Volume21
Issue number3
DOIs
Publication statusPublished - Mar 2015

Keywords

  • TANDEM-REPEAT ANALYSIS
  • MICROARRAY-BASED DETECTION
  • COMPETENCE NETWORK
  • ADULTS
  • CHLAMYDOPHILA
  • PATHOGENS
  • CAPNETZ
  • STRAINS
  • FRANCE
  • EUROPE

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