Molecular ultrasound imaging: a powerful tool for the diagnosis of endothelial dysfunction and arterial inflammation

Adelina Baleanu-Curaj

Research output: ThesisDoctoral ThesisExternal prepared

355 Downloads (Pure)

Abstract

Atheroslerosis is a disease caused by variations in blood perfusion and the accumulation of lipids within vascular wall, causing vessel obstruction. In advanced stages of atherosclerosis, surgical treatment is applied. This research is combining multiphoton-microscopy and ultrasound imaging to detect: 1) the vascular lesions caused by variations in blood perfusion, and 2) vascular recovery after the surgical interventions applied in advanced atherosclerosis. Therefore, the ultrasound imaging was successfully applied in differentiating injured from healthy vessels. Our findings may be beneficial for the development of new diagnostic and treatment protocols for patients with different stages of atherosclerosis.
Original languageEnglish
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • Ramaekers, Frans, Supervisor
  • van Zandvoort, Marc, Supervisor
  • Kiessling, Fabian, Supervisor, External person
Award date2 Nov 2017
Place of PublicationMaastricht
Publisher
Print ISBNs9783000565724
DOIs
Publication statusPublished - 2017

Keywords

  • atherosclerosis
  • blood perfusion
  • vascular lesion
  • surgery

Cite this