Modulation of fat oxidation: nutritional and pharmacological approach

J.G.P. van Can

Research output: ThesisDoctoral ThesisInternal

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Obesity occurs more and more often, both in adults and in children. Obesity increases the risk of developing, for example, diabetes, high blood pressure and cardiovascular diseases. To raise the effectiveness of programmes that are aimed at body weight loss and the prevention of diabetes, extra strategies are necessary. This dissertation presents the effects of two nutrition strategies (changing the type of sugar in nutrition and the use of green tea supplements) and a pharmacological strategy that influence the fat oxidation. Although lifestyle intervention should be the first step in regulating body weight and prevention from diabetes, this approach does not appear effective for everyone. Food supplements or pharmacological interventions can be useful additions to make lifestyle interventions more successful.

Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
  • Blaak, Ellen, Supervisor
  • Saris, Wim, Co-Supervisor
  • van Loon, Lucas, Co-Supervisor
Award date31 Oct 2012
Place of PublicationMaastricht
Publication statusPublished - 1 Jan 2012


  • obesity
  • fat oxidation
  • diabetes
  • nutrition

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