Middellangetermijnoverleving na open versus robotgeassisteerde radicale cystectomie in Nederland: resultaten van de ‘SNAPSHOT’ cystectomie

Noor van Ginkel; André N. Vis; Joost L. Boormans; Henk G. van der Poel; Deric K.E. van der Schoot; Katja K.H. Aben; Tom J.N. Hermans; Dennie Meijer; Jens Voortman; Tom J.H. Arends; Peter J. Ausems; Dorine Baselmans; Christian P.A.M. Berger; Anne Claire Berrens; Henry Bickerstaffe; Siebe D. Bos; Marlene Braam; K. Tim Buddingh; Sebastiaan Claus; Karen Dekker; Thomas van Doeveren; Sarah M.H. Einerhand; Laurent M.C.Laurent Fossion; Florentien J. Hinsenveld; Erik J. van Gennep; Lorena A. Grondhuis Palacios; Mandy M. Hobijn; Suzanne H. van Huystee; Martinique Jaspers-Valentijn; O. Sjoerd Klaver; Evert L. Koldewijn; Linn Korsten; Anne Lenting; Koen J. Lentjes; Henk B. Luiting; Saskia van der Meer; Laura Mertens; Jakko A. Nieuwenhuijzen; M. Arjen Noordzij; Ronald I. Nooter; Marije Notenboom; Robert J.A. Oomen; Joep G.H. van Roermund; Judith de Rooij; Hossain Roshani; Bart P. Schrier; Michelle A. van der Slot; D. M.Rik Somford; Piter Jan Stelwagen; Aukje M.A. Stroux; S.C. Van Beek; Et al.

doi:10.1007/s13629-023-00409-x

Middellangetermijnoverleving na open versus robotgeassisteerde radicale cystectomie in Nederland: resultaten van de ‘SNAPSHOT’ cystectomie

Translated title of the contribution: Intermediate term survival following open versus robot-assisted radical cystectomy in the Netherlands: results of the Cystectomie SNAPSHOT study

Noor van Ginkel, André N. Vis, Joost L. Boormans, Henk G. van der Poel, Deric K.E. van der Schoot, Katja K.H. Aben, Tom J.N. Hermans, Dennie Meijer, Jens Voortman, Tom J.H. Arends, Peter J. Ausems, Dorine Baselmans, Christian P.A.M. Berger, Anne Claire Berrens, Henry Bickerstaffe, Siebe D. Bos, Marlene Braam, K. Tim Buddingh, Sebastiaan Claus, Karen DekkerThomas van Doeveren, Sarah M.H. Einerhand, Laurent M.C.Laurent Fossion, Florentien J. Hinsenveld, Erik J. van Gennep, Lorena A. Grondhuis Palacios, Mandy M. Hobijn, Suzanne H. van Huystee, Martinique Jaspers-Valentijn, O. Sjoerd Klaver, Evert L. Koldewijn, Linn Korsten, Anne Lenting, Koen J. Lentjes, Henk B. Luiting, Saskia van der Meer, Laura Mertens, Jakko A. Nieuwenhuijzen, M. Arjen Noordzij, Ronald I. Nooter, Marije Notenboom, Robert J.A. Oomen, Joep G.H. van Roermund, Judith de Rooij, Hossain Roshani, Bart P. Schrier, Michelle A. van der Slot, D. M.Rik Somford, Piter Jan Stelwagen, Aukje M.A. Stroux, S.C. Van Beek^*, Et al.

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

There is insufficient knowledge on intermediate-term survival of non-metastatic muscle-invasive bladder cancer (MIBC) after open (ORC) versus robot-assisted (RARC) cystectomy, with or without neo-adjuvant chemotherapy (NAC). This retrospective study was performed in 19 Dutch hospitals between 2012 and 2015 to assess the five-year survival after both interventions and the influence of NAC. Out of 1,534 cT1-4N0-1-patients, 1,086 patients were treated with ORC and 389 with RARC. The 5-year survival rate after ORC was 51% (95% CI 47–53) versus 58% after RARC (95% CI 52–63), hazard ratio 1.00 (95% CI 0.84–1.20) after multivariable analysis. 226 of 965 cT2-4aN0 patients were treated with NAC. More patients had ypT0 after NAC than after no NAC (31% vs 15%; p?< 0.01). The best five-year survival was in patients with ypT0 after NAC (89%; 95% CI 81–97). This study shows similar five-year survival of MIBC patients treated with ORC or RARC and shows that the best survival was after NAC.

Translated title of the contribution	Intermediate term survival following open versus robot-assisted radical cystectomy in the Netherlands: results of the Cystectomie SNAPSHOT study
Original language	Dutch
Pages (from-to)	164-175
Number of pages	12
Journal	Tijdschrift voor Urologie
Volume	13
Issue number	8
DOIs	https://doi.org/10.1007/s13629-023-00409-x
Publication status	Published - Dec 2023

Keywords

chemotherapy
muscle-invasive bladdercancer
prognosis
radical cystectomy

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10.1007/s13629-023-00409-xLicence: CC BY

Cite this

van Ginkel, N., Vis, A. N., Boormans, J. L., van der Poel, H. G., van der Schoot, D. K. E., Aben, K. K. H., Hermans, T. J. N., Meijer, D., Voortman, J., Arends, T. J. H., Ausems, P. J., Baselmans, D., Berger, C. P. A. M., Berrens, A. C., Bickerstaffe, H., Bos, S. D., Braam, M., Buddingh, K. T., Claus, S., ... Et al. (2023). Middellangetermijnoverleving na open versus robotgeassisteerde radicale cystectomie in Nederland: resultaten van de ‘SNAPSHOT’ cystectomie. Tijdschrift voor Urologie, 13(8), 164-175. https://doi.org/10.1007/s13629-023-00409-x

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title = "Middellangetermijnoverleving na open versus robotgeassisteerde radicale cystectomie in Nederland: resultaten van de {\textquoteleft}SNAPSHOT{\textquoteright} cystectomie",

abstract = "There is insufficient knowledge on intermediate-term survival of non-metastatic muscle-invasive bladder cancer (MIBC) after open (ORC) versus robot-assisted (RARC) cystectomy, with or without neo-adjuvant chemotherapy (NAC). This retrospective study was performed in 19 Dutch hospitals between 2012 and 2015 to assess the five-year survival after both interventions and the influence of NAC. Out of 1,534 cT1-4N0-1-patients, 1,086 patients were treated with ORC and 389 with RARC. The 5-year survival rate after ORC was 51% (95% CI 47–53) versus 58% after RARC (95% CI 52–63), hazard ratio 1.00 (95% CI 0.84–1.20) after multivariable analysis. 226 of 965 cT2-4aN0 patients were treated with NAC. More patients had ypT0 after NAC than after no NAC (31% vs 15%; p?< 0.01). The best five-year survival was in patients with ypT0 after NAC (89%; 95% CI 81–97). This study shows similar five-year survival of MIBC patients treated with ORC or RARC and shows that the best survival was after NAC.",

keywords = "chemotherapy, muscle-invasive bladdercancer, prognosis, radical cystectomy",

author = "{van Ginkel}, Noor and Vis, {Andr{\'e} N.} and Boormans, {Joost L.} and {van der Poel}, {Henk G.} and {van der Schoot}, {Deric K.E.} and Aben, {Katja K.H.} and Hermans, {Tom J.N.} and Dennie Meijer and Jens Voortman and Arends, {Tom J.H.} and Ausems, {Peter J.} and Dorine Baselmans and Berger, {Christian P.A.M.} and Berrens, {Anne Claire} and Henry Bickerstaffe and Bos, {Siebe D.} and Marlene Braam and Buddingh, {K. Tim} and Sebastiaan Claus and Karen Dekker and {van Doeveren}, Thomas and Einerhand, {Sarah M.H.} and Fossion, {Laurent M.C.Laurent} and Hinsenveld, {Florentien J.} and {van Gennep}, {Erik J.} and {Grondhuis Palacios}, {Lorena A.} and Hobijn, {Mandy M.} and {van Huystee}, {Suzanne H.} and Martinique Jaspers-Valentijn and Klaver, {O. Sjoerd} and Koldewijn, {Evert L.} and Linn Korsten and Anne Lenting and Lentjes, {Koen J.} and Luiting, {Henk B.} and {van der Meer}, Saskia and Laura Mertens and Nieuwenhuijzen, {Jakko A.} and Noordzij, {M. Arjen} and Nooter, {Ronald I.} and Marije Notenboom and Oomen, {Robert J.A.} and {van Roermund}, {Joep G.H.} and {de Rooij}, Judith and Hossain Roshani and Schrier, {Bart P.} and {van der Slot}, {Michelle A.} and Somford, {D. M.Rik} and Stelwagen, {Piter Jan} and Stroux, {Aukje M.A.} and {Van Beek}, S.C. and {Et al.}",

note = "Publisher Copyright: {\textcopyright} 2023, The Author(s).",

year = "2023",

month = dec,

doi = "10.1007/s13629-023-00409-x",

language = "Dutch",

volume = "13",

pages = "164--175",

journal = "Tijdschrift voor Urologie",

issn = "2211-3037",

publisher = "Springer",

number = "8",

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van Ginkel, N, Vis, AN, Boormans, JL, van der Poel, HG, van der Schoot, DKE, Aben, KKH, Hermans, TJN, Meijer, D, Voortman, J, Arends, TJH, Ausems, PJ, Baselmans, D, Berger, CPAM, Berrens, AC, Bickerstaffe, H, Bos, SD, Braam, M, Buddingh, KT, Claus, S, Dekker, K, van Doeveren, T, Einerhand, SMH, Fossion, LMCL, Hinsenveld, FJ, van Gennep, EJ, Grondhuis Palacios, LA, Hobijn, MM, van Huystee, SH, Jaspers-Valentijn, M, Klaver, OS, Koldewijn, EL, Korsten, L, Lenting, A, Lentjes, KJ, Luiting, HB, van der Meer, S, Mertens, L, Nieuwenhuijzen, JA, Noordzij, MA, Nooter, RI, Notenboom, M, Oomen, RJA, van Roermund, JGH, de Rooij, J, Roshani, H, Schrier, BP, van der Slot, MA, Somford, DMR, Stelwagen, PJ, Stroux, AMA, Van Beek, SC & Et al. 2023, 'Middellangetermijnoverleving na open versus robotgeassisteerde radicale cystectomie in Nederland: resultaten van de ‘SNAPSHOT’ cystectomie', Tijdschrift voor Urologie, vol. 13, no. 8, pp. 164-175. https://doi.org/10.1007/s13629-023-00409-x

TY - JOUR

T1 - Middellangetermijnoverleving na open versus robotgeassisteerde radicale cystectomie in Nederland

T2 - resultaten van de ‘SNAPSHOT’ cystectomie

AU - van Ginkel, Noor

AU - Vis, André N.

AU - Boormans, Joost L.

AU - van der Poel, Henk G.

AU - van der Schoot, Deric K.E.

AU - Aben, Katja K.H.

AU - Hermans, Tom J.N.

AU - Meijer, Dennie

AU - Voortman, Jens

AU - Arends, Tom J.H.

AU - Ausems, Peter J.

AU - Baselmans, Dorine

AU - Berger, Christian P.A.M.

AU - Berrens, Anne Claire

AU - Bickerstaffe, Henry

AU - Bos, Siebe D.

AU - Braam, Marlene

AU - Buddingh, K. Tim

AU - Claus, Sebastiaan

AU - Dekker, Karen

AU - van Doeveren, Thomas

AU - Einerhand, Sarah M.H.

AU - Fossion, Laurent M.C.Laurent

AU - Hinsenveld, Florentien J.

AU - van Gennep, Erik J.

AU - Grondhuis Palacios, Lorena A.

AU - Hobijn, Mandy M.

AU - van Huystee, Suzanne H.

AU - Jaspers-Valentijn, Martinique

AU - Klaver, O. Sjoerd

AU - Koldewijn, Evert L.

AU - Korsten, Linn

AU - Lenting, Anne

AU - Lentjes, Koen J.

AU - Luiting, Henk B.

AU - van der Meer, Saskia

AU - Mertens, Laura

AU - Nieuwenhuijzen, Jakko A.

AU - Noordzij, M. Arjen

AU - Nooter, Ronald I.

AU - Notenboom, Marije

AU - Oomen, Robert J.A.

AU - van Roermund, Joep G.H.

AU - de Rooij, Judith

AU - Roshani, Hossain

AU - Schrier, Bart P.

AU - van der Slot, Michelle A.

AU - Somford, D. M.Rik

AU - Stelwagen, Piter Jan

AU - Stroux, Aukje M.A.

AU - Van Beek, S.C.

AU - Et al.

PY - 2023/12

Y1 - 2023/12

N2 - There is insufficient knowledge on intermediate-term survival of non-metastatic muscle-invasive bladder cancer (MIBC) after open (ORC) versus robot-assisted (RARC) cystectomy, with or without neo-adjuvant chemotherapy (NAC). This retrospective study was performed in 19 Dutch hospitals between 2012 and 2015 to assess the five-year survival after both interventions and the influence of NAC. Out of 1,534 cT1-4N0-1-patients, 1,086 patients were treated with ORC and 389 with RARC. The 5-year survival rate after ORC was 51% (95% CI 47–53) versus 58% after RARC (95% CI 52–63), hazard ratio 1.00 (95% CI 0.84–1.20) after multivariable analysis. 226 of 965 cT2-4aN0 patients were treated with NAC. More patients had ypT0 after NAC than after no NAC (31% vs 15%; p?< 0.01). The best five-year survival was in patients with ypT0 after NAC (89%; 95% CI 81–97). This study shows similar five-year survival of MIBC patients treated with ORC or RARC and shows that the best survival was after NAC.

AB - There is insufficient knowledge on intermediate-term survival of non-metastatic muscle-invasive bladder cancer (MIBC) after open (ORC) versus robot-assisted (RARC) cystectomy, with or without neo-adjuvant chemotherapy (NAC). This retrospective study was performed in 19 Dutch hospitals between 2012 and 2015 to assess the five-year survival after both interventions and the influence of NAC. Out of 1,534 cT1-4N0-1-patients, 1,086 patients were treated with ORC and 389 with RARC. The 5-year survival rate after ORC was 51% (95% CI 47–53) versus 58% after RARC (95% CI 52–63), hazard ratio 1.00 (95% CI 0.84–1.20) after multivariable analysis. 226 of 965 cT2-4aN0 patients were treated with NAC. More patients had ypT0 after NAC than after no NAC (31% vs 15%; p?< 0.01). The best five-year survival was in patients with ypT0 after NAC (89%; 95% CI 81–97). This study shows similar five-year survival of MIBC patients treated with ORC or RARC and shows that the best survival was after NAC.

KW - chemotherapy

KW - muscle-invasive bladdercancer

KW - prognosis

KW - radical cystectomy

U2 - 10.1007/s13629-023-00409-x

DO - 10.1007/s13629-023-00409-x

M3 - Article

SN - 2211-3037

VL - 13

SP - 164

EP - 175

JO - Tijdschrift voor Urologie

JF - Tijdschrift voor Urologie

IS - 8

ER -