Abstract
Objectives The present study is a systematic review conducted as part of a methodological approach to develop evidence-based recommendations for economic evaluations in spine surgery. The aim of this systematic review is to evaluate the methodology and quality of currently available clinical cost-effectiveness studies in spine surgery.Study design Systematic literature review.Data sources PubMed, Web of Science, Embase, Cochrane, Cumulative Index to Nursing and Allied Health Literature, EconLit and The National Institute for Health Research Economic Evaluation Database were searched through 8 December 2022.Eligibility criteria for selecting studies Studies were included if they met all of the following eligibility criteria: (1) spine surgery, (2) the study cost-effectiveness and (3) clinical study. Model-based studies were excluded.Data extraction and synthesis The following data items were extracted and evaluated: pathology, number of participants, intervention(s), year, country, study design, time horizon, comparator(s), utility measurement, effectivity measurement, costs measured, perspective, main result and study quality.Results 130 economic evaluations were included. Seventy-four of these studies were retrospective studies. The majority of the studies had a time horizon shorter than 2 years. Utility measures varied between the EuroQol 5 dimensions and variations of the Short-Form Health Survey. Effect measures varied widely between Visual Analogue Scale for pain, Neck Disability Index, Oswestry Disability Index, reoperation rates and adverse events. All studies included direct costs from a healthcare perspective. Indirect costs were included in 47 studies. Total Consensus Health Economic Criteria scores ranged from 2 to 18, with a mean score of 12.0 over all 130 studies.Conclusions The comparability of economic evaluations in spine surgery is extremely low due to different study designs, follow-up duration and outcome measurements such as utility, effectiveness and costs. This illustrates the need for uniformity in conducting and reporting economic evaluations in spine surgery.
Original language | English |
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Article number | e067871 |
Number of pages | 13 |
Journal | BMJ Open |
Volume | 13 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Feb 2023 |
Keywords
- Health economics
- Spine
- Economics
- COST-UTILITY ANALYSIS
- LUMBAR INTERBODY FUSION
- ANTERIOR CERVICAL DISKECTOMY
- TOTAL DISC REPLACEMENT
- CARE RESOURCE UTILIZATION
- ADJACENT-SEGMENT DISEASE
- DEGENERATIVE-SPONDYLOLISTHESIS
- INSTRUMENTED FUSION
- SURGICAL-TREATMENT
- MULTILEVEL HEMILAMINECTOMY