Metformin-associated lactic acidosis in a patient with normal kidney function.

T.T. van Sloten, E. Pijpers, C.D.A. Stehouwer, M.C. Brouwers*

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review


The existence of metformin-induced lactic acidosis has been questioned, in particular in the absence of specific risk factors such as impaired renal function. This report describes the presence of lactic acidosis in a patient with normal kidney function and normal doses of metformin. Subsequent positive rechallenge with metformin confirms causality.
Original languageEnglish
Pages (from-to)E57-E58
Number of pages2
JournalDiabetes Research and Clinical Practice
Issue number3
Publication statusPublished - Jun 2012


  • Metformin
  • Biguanides
  • Treatment type 2 diabetes

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