Metabolic Modeling Combined With Machine Learning Integrates Longitudinal Data and Identifies the Origin of LXR-Induced Hepatic Steatosis

N.A.W. van Riel, C.A. Tiemann, P.A.J. Hilbers, A.K. Groen

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number536957
Number of pages18
JournalFrontiers in bioengineering and biotechnology
Publication statusPublished - 16 Feb 2021


  • cholesterol
  • longitudinal trajectory modeling
  • lxr agonist
  • machine learning
  • mechanistic modeling
  • regularization
  • systems biology
  • uncertainty quantification
  • LXR agonist

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