Management of Progressive Pulmonary Nodules Found during and outside of CT Lung Cancer Screening Studies

Mathias Meyer*, Rozemarijn Vliegenthart, Thomas Henzler, Daniel Buergy, Frank A. Giordano, Michael Kostrzewa, Nils Rathmann, Odd Terje Brustugun, Lucio Crino, Anne-Marie C. Dingemans, Michael Dusmet, Dean Fennell, Dominique Grunenwald, Rudolf Maria Huber, Marcin Moniuszko, Francoise Mornex, Mauro Papotti, Lothar Pilz, Suresh Senan, Kostas SyrigosMaurice Perol, Jhanelle E. Gray, Christoph Schabel, Jan R. van Meerbeeck, Nico van Zandwijk, Cai Cun Zhou, Christian Manegold, Wieland Voigt, Eric Dominic Roessner

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

6 Citations (Web of Science)

Abstract

Although the effectiveness of screening for lung cancer remains controversial, it is a fact that most lung cancers are diagnosed at an advanced stage outside of lung cancer screening programs. In 2013, the U.S. Preventive Services Task Force revised its lung cancer screening recommendation, now supporting lung cancer screening by low-dose computed tomography in patients at high risk This is also endorsed by many major medical societies and advocacy group stake-holders, albeit with different eligibility criteria. In Europe, population-based lung cancer screening has so far not been recommended or implemented, as some important issues remain unresolved. Among them is the open question of how enlarging pulmonary nodules detected in lung cancer screening should be managed. This article comprises two parts: a review of the current lung cancer screening approaches and the potential therapeutic options for enlarging pulmonary nodules, followed by a meeting report including consensus statements of an interdisciplinary expert panel that discussed the potential of the different therapeutic options. 2017 International Association for the Study of Lung Cancer. (C) Published by Elsevier Inc. All rights reserved.

Original languageEnglish
Pages (from-to)1755-1765
Number of pages11
JournalJournal of Thoracic Oncology
Volume12
Issue number12
DOIs
Publication statusPublished - Dec 2017

Keywords

  • Pulmonary nodules
  • Lung cancer screening
  • Surgery
  • Stereotactic ablative radiotherapy
  • STEREOTACTIC ABLATIVE RADIOTHERAPY
  • BODY RADIATION-THERAPY
  • CLINICAL-PRACTICE GUIDELINES
  • ED AMERICAN-COLLEGE
  • SHORT HOOK WIRE
  • PHASE-II TRIAL
  • STAGE-I
  • RADIOFREQUENCY ABLATION
  • CHEST PHYSICIANS
  • ESTS GUIDELINES

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